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General Medicine

Lymphogranuloma Venereum

Greta M. Josephson, DO and Saira Ajmal, MD Reviewed 06/2019
 


BASICS

Lymphogranuloma venereum (LGV) is an uncommon systemic sexually transmitted infection (STI) caused by Chlamydia trachomatis. Classically endemic in tropical regions, Europe and North America ha...

DIAGNOSIS

History, physical examination, and diagnostic exclusion are important factors in the diagnosis of LGV. 

HISTORY

Recent unprotected anogenital intercourse (3- to 30-day incubation period), ofte...

TREATMENT

Oral antibiotics administered in an ambulatory setting are effective in most uncomplicated cases. 

GENERAL MEASURES

Avoid all sexual contact once lesions appear and until test of cure is negat...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patients should be observed until symptom free. Test of cure is recommended 3 to 5 weeks after completion of treatment. Ensure partner’s treatment and test of cur...

REFERENCES

1
European Centre for Disease Prevention and Control. Lymphogranuloma venereum—Annual Epidemiological Report 2016 [2014 data]. https://ecdc.europa.eu/en/publications-data/lymphogranuloma-ven...

ADDITIONAL READING

  • Juzlova K, Rob F, Zakoucka H, et al. The first case of lymphogranuloma venereum in a woman in East-Central Europe and its multiple co-infections. Folia Microbiol (Praha).  2018...

CODES

ICD10

A55 Chlamydial lymphogranuloma (venereum) 

ICD9

099.1 Lymphogranuloma venereum 

SNOMED

186946009 Lymphogranuloma venereum (disorder) 

CLINICAL PEARLS

  • Consider high-risk populations when deciding to screen patients: MSM, HIV positive.

  • In MSM population, proctitis rather than classic inguinal lymphadenopathy is the most common presenta...

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Related Images
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Primary lesion of lymphogranuloma venereum.
Primary lesion of lymphogranuloma venereum.
Lymphogranuloma venereum of vulva.
Lymphogranuloma venereum of vulva.
Lymphogranuloma venereum. Painful inguinal lymphadenopathy in a man infected with C. trachomatis.
Lymphogranuloma venereum. Painful inguinal lymphadenopathy in a man infected with C. trachomatis.
Grooved nodes (saddle nodes) characteristic of lymphogranuloma venereum.
Grooved nodes (saddle nodes) characteristic of lymphogranuloma venereum.
Figure 107.4. Genital ulcers. (A) The eroded purulent ulcer of chancroid is painful and may be associated with painful inguinal adenitis. (B) Lymphogranuloma venereum has a small, transient genital ulcer with swollen, extremely painful inguinal lymph nodes. (C) The genital lesions of GI are painless, beefy red, raised lesions. (Part C from Al-Harmozi SA, el-Tonsy MH. Granulmoa inguinale. Report of the first case in Qatar. Sex Transm Dis1986;13:102, with permission.)
Figure 107.4. Genital ulcers. (A) The eroded purulent ulcer of chancroid is painful and may be associated with painful inguinal adenitis. (...
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