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General Medicine

Lymphogranuloma Venereum

Reviewed 06/2018
 


BASICS

Lymphogranuloma venereum (LGV) is an uncommon systemic sexually transmitted infection (STI) caused by Chlamydia trachomatis. The incidence of LGV continues to increase in Europe, especially amo...

DIAGNOSIS

History, physical examination, and diagnostic exclusion are important factors in the diagnosis of LGV. 

HISTORY

Recent unprotected anogenital intercourse (3- to 30-day incubation period), ofte...

TREATMENT

Oral antibiotics administered in an ambulatory setting are effective in most uncomplicated cases. 

GENERAL MEASURES

Avoid all sexual contact once lesions appear and until test of cure is negat...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patients should be observed until symptom-free. Test of cure is recommended 3 to 5 weeks after treatment. Ensure partner's treatment and test of care. 

Patient Monitoring

REFERENCES

1
Ceovic R, Gulin SJ. Lymphogranuloma venereum: diagnostic and treatment challenges. Infect Drug Resist.  2015;8:39–47. [View Abstract on OvidMedline]
2
Desclaux A, Touati A, Neau D, et a...

ADDITIONAL READING

  • Juzlova K, Rob F, Zakoucka H, et al. The first case of lymphogranuloma venereum in a woman in East-Central Europe and its multiple co-infections. Folia Microbiol (Praha).  2018...

CODES

ICD10

A55 Chlamydial lymphogranuloma (venereum) 

ICD9

099.1 Lymphogranuloma venereum 

SNOMED

186946009 Lymphogranuloma venereum (disorder) 

CLINICAL PEARLS

  • Consider high-risk populations when deciding to screen patients: MSM, HIV positive.

  • In MSM presenting with colorectal symptoms (tenesmus, constipation, anal discharge, and weight loss),...

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Related Images
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Primary lesion of lymphogranuloma venereum.
Primary lesion of lymphogranuloma venereum.
Lymphogranuloma venereum of vulva.
Lymphogranuloma venereum of vulva.
Lymphogranuloma venereum. Painful inguinal lymphadenopathy in a man infected with C. trachomatis.
Lymphogranuloma venereum. Painful inguinal lymphadenopathy in a man infected with C. trachomatis.
Grooved nodes (saddle nodes) characteristic of lymphogranuloma venereum.
Grooved nodes (saddle nodes) characteristic of lymphogranuloma venereum.
Figure 107.4. Genital ulcers. (A) The eroded purulent ulcer of chancroid is painful and may be associated with painful inguinal adenitis. (B) Lymphogranuloma venereum has a small, transient genital ulcer with swollen, extremely painful inguinal lymph nodes. (C) The genital lesions of GI are painless, beefy red, raised lesions. (Part C from Al-Harmozi SA, el-Tonsy MH. Granulmoa inguinale. Report of the first case in Qatar. Sex Transm Dis1986;13:102, with permission.)
Figure 107.4. Genital ulcers. (A) The eroded purulent ulcer of chancroid is painful and may be associated with painful inguinal adenitis. (...
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