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Lymphogranuloma Venereum

Greta M. Josephson, DO and Saira Ajmal, MD Reviewed 06/2019
 


BASICS

Lymphogranuloma venereum (LGV) is an uncommon systemic sexually transmitted infection (STI) caused by Chlamydia trachomatis. Classically endemic in tropical regions, Europe and North America ha...

DIAGNOSIS

History, physical examination, and diagnostic exclusion are important factors in the diagnosis of LGV. 

HISTORY

Recent unprotected anogenital intercourse (3- to 30-day incubation period), ofte...

TREATMENT

Oral antibiotics administered in an ambulatory setting are effective in most uncomplicated cases. 

GENERAL MEASURES

Avoid all sexual contact once lesions appear and until test of cure is negat...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patients should be observed until symptom free. Test of cure is recommended 3 to 5 weeks after completion of treatment. Ensure partner’s treatment and test of cur...

REFERENCES

1
European Centre for Disease Prevention and Control. Lymphogranuloma venereum—Annual Epidemiological Report 2016 [2014 data]. https://ecdc.europa.eu/en/publications-data/lymphogranuloma-ven...

ADDITIONAL READING

  • Juzlova K, Rob F, Zakoucka H, et al. The first case of lymphogranuloma venereum in a woman in East-Central Europe and its multiple co-infections. Folia Microbiol (Praha).  2018...

CODES

ICD10

A55 Chlamydial lymphogranuloma (venereum) 

ICD9

099.1 Lymphogranuloma venereum 

SNOMED

186946009 Lymphogranuloma venereum (disorder) 

CLINICAL PEARLS

  • Consider high-risk populations when deciding to screen patients: MSM, HIV positive.

  • In MSM population, proctitis rather than classic inguinal lymphadenopathy is the most common presenta...

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