Infection with Plasmodium species protozoa, transmitted to humans by Anopheles spp. mosquitoes
Most morbidity and mortality is caused by Plasmodium falciparum.
Nonimmune individuals ar...
Initial malaria symptoms are nonspecific. Suspect malaria in ill patients returning from endemic area with:
Fever, malaise, myalgias, chills, headache, nausea, splenomegaly (with chron...
PO therapy for uncomplicated chloroquine-resistant P. falciparum (most P. falciparum), chloroquine-resistant P. vivax (see “For uncomplicated chloroquine-sensitive P. viv...
Malaria chemoprophylaxis prior to travel
Travel information may be obtained at the CDC travel Web site: http://www.cdc.gov/travel.
B51.9 Plasmodium vivax malaria without complication
B50.9 Plasmodium falciparum malaria, unspecified
B52 Plasmodium malariae malaria
B53.0 Plasmodium ovale malaria
B52.0 Plasmodium malariae mal...
Test for malaria in travelers returning from endemic areas presenting with fever or flulike illness.
Early identification and aggressive treatment of persons with malaria is essential.
C...
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Figure 16.17. A thin blood smear shows several P. falciparum-infected erythrocytes. One erythrocyte has a ring form along its edge (appliqué form), and the other has a ring form that contains double dots of chromatin (arrow). Giemsa, 3400.
Figure 16.17. A thin blood smear shows several P. falciparum-infected erythrocytes. One erythrocyte has a ring form along its edge (appli...
Figure 16.24. A blood film from a patient with P. vivax infection shows two microgametocytes and several ring forms. The microgametocytes have large nuclei with loose chromatin (arrow). Giemsa, 3400.
Figure 16.24. A blood film from a patient with P. vivax infection shows two microgametocytes and several ring forms. The microgametocytes...
Life cycle of malaria. An Anopheles mosquito bites an infected person, taking blood that contains micro- and macrogametocytes (sexual forms). In the mosquito, sexual multiplication ("sporogony") produces infective sporozoites in the salivary glands. (1) During the mosquito bite, sporozoites are inoculated into the bloodstream of the vertebrate host. Some sporozoites leave the blood and enter the hepatocytes, where they multiply asexually (exoerythrocytic schizogony), and form thousands of u...
Life cycle of malaria. An Anopheles mosquito bites an infected person, taking blood that contains micro- and macrogametocytes (sexual form...