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Malaria

Kathrine R. Tan, MD, MPH Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Acute or chronic infection transmitted to humans by Anopheles spp. mosquitoes

  • Most morbidity and mortality is caused by Plasmodium falciparum. An estimated 216 million cases occur ann...

DIAGNOSIS

HISTORY

  • Initial malaria symptoms are nonspecific. Suspect malaria in ill patients returning from endemic area with:

    • Fever, malaise, myalgias, chills, headache, nausea, splenomegaly (with chron...

TREATMENT

MEDICATION

First Line

  • For uncomplicated chloroquine-resistant P. falciparum (most P. falciparum), chloroquine-resistant P. vivax (New Guinea has highest rates of chloroquine-resistant P. vivax...

ONGOING CARE

PATIENT EDUCATION

  • Malaria chemoprophylaxis prior to travel

  • Travel information may be obtained at the CDC travel Web site: http://www.cdc.gov/travel.

PROGNOSIS

Malaria infection (particularly ...

REFERENCES

1
World Health Organization. World Malaria Report 2017. Geneva, Switzerland: WHO Press; 2017. [View Abstract on OvidMedline]
2
Mace KE, Arguin PM, Tan KR. Malaria surveillance—United States, 2...

ADDITIONAL READING

Centers for Disease Control and Prevention. Infectious diseases related to travel. https://wwwnc.cdc.gov/travel/yellowbook/2018/infectious-diseases-related-to-travel/malaria#1939. A...

CODES

ICD10

  • B54 Unspecified malaria

  • B50.9 Plasmodium falciparum malaria, unspecified

  • B51.9 Plasmodium vivax malaria without complication

  • B53.0 Plasmodium ovale malaria

  • B52.9 Plasmodium malariae malaria wit...

CLINICAL PEARLS

  • Consider malaria in travelers returning from endemic areas presenting with fever or flulike illness.

  • Early identification and aggressive treatment of persons with suspected or confirmed...

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