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Malaria

Paul M. Arguin, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Acute or chronic infection transmitted to humans by Anopheles spp. mosquitoes

  • Most morbidity and mortality is caused by Plasmodium falciparum. An estimated 212 million cases occur ann...

DIAGNOSIS

HISTORY

  • Initial symptoms of malaria are nonspecific. Suspect malaria in ill patients returning from endemic area with

    • Fever, malaise, myalgias, chills, headache, nausea, splenomegaly (with c...

TREATMENT

MEDICATION

First Line

  • For uncomplicated chloroquine-resistant P. falciparum (most P. falciparum), chloroquine-resistant P. vivax, or when species is unknown, the following regimens are recomme...

ONGOING CARE

PATIENT EDUCATION

REFERENCES

1
World Health Organization. World Malaria Report 2016. Geneva, Switzerland: WHO Press; 2016.
2
Mace KE, Arguin PM. Malaria surveillance—United States, 2014. MMWR Surveil Summ.  2017;66(1...

ADDITIONAL READING

CODES

ICD10

  • B54 Unspecified malaria

  • B50.9 Plasmodium falciparum malaria, unspecified

  • B51.9 Plasmodium vivax malaria without complication

  • B53.0 Plasmodium ovale malaria

  • B52.9 Plasmodium malariae malaria wit...

CLINICAL PEARLS

  • Consider malaria in travelers returning from endemic areas presenting with fever or flulike illness.

  • Early identification (sometimes requiring a high index of suspicion) and aggressive ...

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