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Malaria

Kathrine R. Tan, MD, MPH and Francisca Abanyie-Bimbo, MD, MPH Reviewed 06/2020
 


BASICS

DESCRIPTION

  • Infection with Plasmodium species protozoa, transmitted to humans by Anopheles spp. mosquitoes

  • Most morbidity and mortality is caused by Plasmodium falciparum.

  • Nonimmune individuals ar...

DIAGNOSIS

HISTORY

  • Initial malaria symptoms are nonspecific. Suspect malaria in ill patients returning from endemic area with:

    • Fever, malaise, myalgias, chills, headache, nausea, splenomegaly (with chron...

TREATMENT

MEDICATION

First Line

  • PO therapy for uncomplicated chloroquine-resistant P. falciparum (most P. falciparum), chloroquine-resistant P. vivax (see “For uncomplicated chloroquine-sensitive P. viv...

ONGOING CARE

PATIENT EDUCATION

  • Malaria chemoprophylaxis prior to travel

  • Travel information may be obtained at the CDC travel Web site: http://www.cdc.gov/travel.

PROGNOSIS

Malaria infection (particularly ...

REFERENCES

1
Centers for Disease Control and Prevention. Malaria–Diagnosis & Treatment in the United States. https://www.cdc.gov/malaria/diagnosis_treatment/index.html. Accessed September 21, 2019.

CODES

ICD10

  • B51.9 Plasmodium vivax malaria without complication

  • B50.9 Plasmodium falciparum malaria, unspecified

  • B52 Plasmodium malariae malaria

  • B53.0 Plasmodium ovale malaria

  • B52.0 Plasmodium malariae mal...

CLINICAL PEARLS

  • Test for malaria in travelers returning from endemic areas presenting with fever or flulike illness.

  • Early identification and aggressive treatment of persons with malaria is essential.

  • C...

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