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Marijuana (Cannabis) Use Disorder

Jason Edward Lambrecht, FACP, PharmD, MD, FHM, Paul G. Millner, MD and Bradley DeVrieze, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Marijuana use leading to clinically significant impairment or distress, manifested by two or more of the following symptoms within a 12-month period:

    • Consumption of larger amounts ove...

DIAGNOSIS

  • USPSTF guidelines encourage screening adults for drug use .

  • Ask for frequency and amount used (e.g., “How often do you use marijuana? Daily? Weekly?”; “How long does a typical ‘eighth’ [1/8 o...

TREATMENT

  • There are no FDA approved medications for the treatment of CUD . There is insufficient evidence to recommend for or against pharmacotherapy for CUD (2).

  • No specific treatment guidelines for ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Monitor cessation by testing urine over several weeks for the inactive cannabis metabolites (carboxy-THC).

  • Drug screening of heavy smokers may remain positive for ...

REFERENCES

1
Boehnke KF, Dean O, Haffajee RL, et al. U.S. Trends in Registration for Medical Cannabis and Reasons for Use from 2016 to 2020. Ann Intern Med. 2022;175:945-951.
2
Perry C, Liberto J, Millik...

CODES

ICD10

  • F12.10 Cannabis abuse, uncomplicated

  • F12.20 Cannabis dependence, uncomplicated

  • F12.288 Cannabis dependence with other cannabis-induced disorder

  • F12.159 Cannabis abuse with psychotic disorder, ...

CLINICAL PEARLS

  • It is estimated that 4.5 to 7 million persons in the U.S. meet criteria for CUD

  • Acute marijuana intoxication is manifested by conjunctival injection, increased heart rate, euphoria, hei...

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