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Meningococcal Disease

Han Q. Bui, MD, MPH Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Meningococcemia is a blood-borne infection caused by Neisseria meningitidis.

  • Bacteremia without meningitis: Patient is acutely ill and may have skin manifestations (rashes, petechiae,...

DIAGNOSIS

HISTORY

  • Symptoms

    • Sudden onset of fever, nausea, vomiting, headache, myalgias, chills, rigor, and/or sore throat (nonsuppurative)

      • Pharyngitis may be mistaken for streptococcal pharyngitis.

      • My...

TREATMENT

MEDICATION

First Line

  • Antibiotics

    • Begin treatment as soon as meningococcal meningitis is suspected.

    • Age guides empiric treatment.

ONGOING CARE

PATIENT EDUCATION

Educate family and close contacts regarding the risk of contracting meningococcal infection. 

PROGNOSIS

Overall mortality is 13%. 

COMPLICATIONS

  • DIC

  • Acute tubular necrosis

  • Neur...

REFERENCES

1
Centers for Disease Control and Prevention. Meningococcal disease. https://www.cdc.gov/meningococcal/clinical-info.html. Accessed July 29, 2017.
2
Gardner P. Clinical practice. Prevention of...

ADDITIONAL READING

  • Visintin C, Mugglestone MA, Fields EJ, et al. Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance. BMJ.  201...

CODES

ICD10

  • A39.4 Meningococcemia, unspecified

  • A39.0 Meningococcal meningitis

  • A39.2 Acute meningococcemia

  • A39.9 Meningococcal infection, unspecified

  • A39.3 Chronic meningococcemia

  • A39.89 Other meningococcal ...

CLINICAL PEARLS

  • Invasive meningococcal disease can be rapidly fatal. Rapid identification and early treatment is essential to promote good clinical outcomes. Treat then test in suspected cases.

  • Provide...

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