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Mild Cognitive Impairment

Birju B. Patel, FACP, MD and N Wilson Holland, FACP, MD Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Mild cognitive impairment (MCI) is defined as significant cognitive impairment in the absence of dementia, as measured by standard memory tests:

    • Concern regarding change in cognition

    • P...

DIAGNOSIS

HISTORY

  • Focus on cognitive deficits and impairment. MCI is meant to reflect a change in cognition and not lifelong impaired cognition.

  • Review all medications that may affect cognition with emp...

TREATMENT

GENERAL MEASURES

Atherosclerotic risk factors should be treated aggressively. 

MEDICATION

The use of cholinesterase inhibitors (ChEIs) in MCI is not associated with any delay in the onset of Al...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Re-evaluate every 6 to 12 months to determine if symptoms are progressing. 

Patient Monitoring

Appropriate cognitive and functional testing should be used to evalua...

REFERENCES

1
Petersen  RC, Lopez  O, Armstrong  MJ, et al. Practice guideline update summary: mild cognitive impairment: report of the Guideline Development, Dissemination, and ...

CODES

ICD10

G31.84 Mild cognitive impairment, so stated 

SNOMED

  • 386805003 Mild cognitive disorder (disorder)

  • 231448004 Age-associated memory impairment (disorder)

CLINICAL PEARLS

  • Amnestic MCI affects primarily memory and is more likely to progress to Alzheimer dementia.

  • Screen for reversible factors, particularly anticholinergic medications, depression, and slee...

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