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Mild Cognitive Impairment

Birju B. Patel, MD, FACP, AGSF and N. Wilson Holland, MD, FACP Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Mild cognitive impairment (MCI) is defined as significant cognitive impairment in the absence of dementia, as measured by standard memory tests:

    • Concern regarding change in cognition

    • P...

DIAGNOSIS

HISTORY

  • Focus on cognitive deficits and impairment. MCI is meant to reflect a change in cognition and not lifelong impaired cognition.

  • Review all medications that may affect cognition; give em...

TREATMENT

GENERAL MEASURES

Atherosclerotic risk factors should be treated aggressively. 

MEDICATION

The use of cholinesterase inhibitors (ChEIs) in MCI is not associated with any delay in the onset of Al...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patients should be reevaluated every 6 to 12 months to determine if symptoms are progressing. 

Patient Monitoring

Appropriate cognitive and functional testing shoul...

REFERENCES

1
Petersen RC, Lopez O, Armstrong MJ, et al. Practice guideline update summary: mild cognitive impairment: report of the Guideline Development, Dissemination, and Implementation Subcommittee...

ADDITIONAL READING

Sanford AM. Mild cognitive impairment. Clin Geriatr Med.  2017;33(3):325–337. [View Abstract on OvidMedline] 

CODES

ICD10

G31.84 Mild cognitive impairment, so stated 

ICD9

331.83 Mild cognitive impairment, so stated 

SNOMED

  • 386805003 Mild cognitive disorder (disorder)

  • 231448004 Age-associated memory impairment (dis...

CLINICAL PEARLS

  • Amnestic MCI affects primarily memory and is more likely to progress to Alzheimer dementia.

  • Screen for reversible factors, particularly anticholinergic medications, depression, and slee...

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