Milk-alkali syndrome results from ingestion of excessive amounts of calcium and absorbable alkali (e.g., bicarbonate and citrate salts)
Historically seen during self-treatment of indi...
Calcium-containing supplement use
Symptoms of hypercalcemia (“stones, bones, moans, groans and behavioral health overtones”):
Nausea, vomiting, constipation, abdominal pain
Polyuria
Menta...
Stop calcium and alkali (carbonate salts):
Supplements
Over-the-counter antacids
Volume expansion
To maintain urine output of 3 L/day
Treat hypercalcemia:
Hydra...
Kidney function
Fluid intake and output
Correction of calcium after treatment
Increase oral fluid intake.
Stop calcium and vitamin D supplementa...
Goltzman D. Nonparathyroid Hypercalcemia. Front Horm Res. 2019;51:77-90.
Malcolm OT. Identification, treatment, and prevent...
Aggressive over-the-counter antacid or calcium supplement use can lead to hypercalcemia.
Calcium supplementation should not exceed 1.2 g/day.
Treat by stopping excess antacid/supplement ...
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