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Mitral Regurgitation

Yongkasem Vorasettakarnkij, MSc, MD Reviewed 06/2021
 


BASICS

DESCRIPTION

  • Disorder of mitral valve (MV) closure, either primary, secondary (functional), or mixed, resulting in a backflow of the left ventricular (LV) stroke volume into the left atrium (LA);...

DIAGNOSIS

HISTORY

  • Associated conditions: RHD, prior MI, connective tissue disorder

  • Acute MR

    • Sudden onset of dyspnea

    • Orthopnea, paroxysmal nocturnal dyspnea

  • Chronic MR

    • Exertional dyspnea, fatigue

    • Palpitation:...

TREATMENT

MEDICATION

  • Acute, severe MR

    • Medical therapy has a limited role and is aimed to stabilize hemodynamics preoperatively.

    • Vasodilators (nitroprusside, nicardipine): to improve hemodynamic compensat...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Chronic MR: asymptomatic 
  • Mild MR with normal LV size and function and no pulmonary hypertension: annual clinical evaluation and TTE every 3 to 5 years or more fre...

REFERENCES

1
Enriquez-Sarano  M, Akins  CW, Vahanian  A. Mitral regurgitation. Lancet.  2009;373(9672):1382–1394. [View Abstract on OvidMedline]
2
...

ADDITIONAL READING

  • El Sabbagh A, Reddy  YNV, Nishimura RA. Mitral valve regurgitation in the contemporary era: insights into diagnosis, management, and future directions. JA...

CODES

ICD10

  • I34.0 Nonrheumatic mitral (valve) insufficiency

  • I05.1 Rheumatic mitral insufficiency

  • Q23.3 Congenital mitral insufficiency

SNOMED

  • 48724000 Mitral valve regurgitation (disorder)

  • 31085000 Rheumati...

CLINICAL PEARLS

  • Follow-up for mild to moderate MR: serial exam and/or echo (mild, every 3 to 5 years, moderate 1 to 2 years) unless LV structural changes

  • Severe MR is usually managed with MV repair.

  • End...

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