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Mitral Valve Prolapse

Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Mitral valve prolapse (MVP) is a systolic billowing of one or both mitral leaflets into the left atrium (LA) during systole ± mitral regurgitation (MR).

  • More specifically, MVP is a si...

DIAGNOSIS

Physical exam and echocardiography 

HISTORY

  • Most patients are asymptomatic.

  • The most frequent symptom is palpitations.

  • Symptoms related to autonomic dysfunction

    • Anxiety and panic attacks

    • Arrhythmi...

TREATMENT

GENERAL MEASURES

Treat MVP with orthostatic symptoms by liberalizing fluid and salt intake. If severe, mineralocorticoids may rarely be used. Support stockings may also be beneficial; in the ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Asymptomatic MVP patients with no significant MR can be followed clinically every 3 to 5 years (3)[C].

  • Patients who are symptomatic or have high-risk features on i...

REFERENCES

1
Delling FN, Vasan RS. Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. Circulation.  2014;129(21):2158–...

ADDITIONAL READING

Otto CM, Bonow RO, eds. Valvular Heart Disease: A Companion to Braunwald’s Heart Disease. 4th ed. Philadelphia, PA: Elsevier; 2014. [View Abstract on OvidMedline] 

CODES

ICD10

I34.1 Nonrheumatic mitral (valve) prolapse 

ICD9

424.0 Mitral valve disorders 

SNOMED

  • 409712001 mitral valve prolapse (disorder)

  • 250989005 Mitral cusp prolapse (disorder)

  • 703359009 Degenerative m...

CLINICAL PEARLS

  • MVP patients may have orthostatic hypotension and tachycardia.

  • Asymptomatic MVP patients with no significant MR can be followed clinically every 3 to 5 years. Patients who are symptomat...

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