A benign inflammatory skin disorder leading to excessive collagen deposition resulting in thickening and sclerosis of the skin and subcutaneous tissues with characteristic plaque for...
Patient describes slowly progressive skin changes over months. Coin-sized lesions slowly enlarge over weeks to months.
Rarely, the lesions can cause some discomfort.
Usually, there are ...
Topical local agents should be considered for superficial lesions that do not cross the joint surface, while deeper and joint crossing lesions favor oral systemic therapies
Active l...
L94.0 Localized scleroderma [morphea]
L94.1 Linear scleroderma
201049004 Morphea (disorder)
128458002 plaque morphea (disorder)
7513007 Generalized morphea
22784002 Linear scleroderma (dis...
Morphea lesions are well-circumscribed plaques that are firm, waxy, and have an ivory color. They are usually multiple, start small, and may slowly enlarge over time. Presence on the t...
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<bold>FIG. 77.2.</bold> Face of a 19-year-old woman with diffuse cutaneous systemic sclerosis. Note loss of normal skin folds and retraction of lips.
<bold>FIG. 77.2.</bold> Face of a 19-year-old woman with diffuse cutaneous systemic sclerosis. Note loss of normal skin folds ...
<bold>FIG. 77.6.</bold> Close-up hand roentgenogram of a 46-year-old woman with limited cutaneous systemic sclerosis. Note extensive subcutaneous calcinosis.
<bold>FIG. 77.6.</bold> Close-up hand roentgenogram of a 46-year-old woman with limited cutaneous systemic sclerosis. Note ext...
<bold>FIG. 77.11.</bold> Photomicrograph of the lung of a 52-year-old woman with diffuse cutaneous systemic sclerosis who died as the result of respiratory insufficiency. Note the dramatic interstitial fi osis and dilatation of air sacs (honeycomb lung).
<bold>FIG. 77.11.</bold> Photomicrograph of the lung of a 52-year-old woman with diffuse cutaneous systemic sclerosis who died...
<bold>FIG. 77.20.</bold> A child with linear scleroderma involving the left lower extremity with evidence of a left knee flexion contracture. There is a plaque of morphea on the right thigh.
<bold>FIG. 77.20.</bold> A child with linear scleroderma involving the left lower extremity with evidence of a left knee flexi...
FIG. 2.17. Juvenile dermatomyositis and scleroderma. A: Atrophic, hypopigmented lesions overlying extensor surfaces of interphalangeal joints, with periungual erythema typical of juvenile dermatomyositis. B: Linear scleroderma involving left lower extremity in a 12-year-old girl.
FIG. 2.17. Juvenile dermatomyositis and scleroderma. A: Atrophic, hypopigmented lesions overlying extensor surfaces of interphalangeal joi...
Scleroderma. The dermis is characterized by large reticular dermal collagen bundles that are oriented parallel to the epidermis. The large size and loss of basket-weave pattern of these collagen bundles are abnormal. No appendages are apparent, as these are destroyed in the disease process.
Scleroderma. The dermis is characterized by large reticular dermal collagen bundles that are oriented parallel to the epidermis. The large...
scleroderma: early stage
Scleroderma: hand, amputated distal digits
Figure 10-195 <bold>SCLERODERMA: ACROOSTEOLYSIS. A. PA Hand.</bold> Note the early resorption of the distal tufts (<italic>arrows</bold>). Incidentally noted is a bandage (<italic>arrowhead</bold>). <bold>B. PA Hand.</bold> Observe the advanced resorption of the distal tufts.
Figure 10-195 <bold>SCLERODERMA: ACROOSTEOLYSIS. A. PA Hand.</bold> Note the early resorption of the distal tufts (<italic...
Linear scleroderma: leg
Morphea: abdomen