Multiple myeloma (MM) is a clonal proliferation of malignant plasma cells.
This clonal proliferation in the bone marrow (BM) can cause extensive skeletal destruction with osteolytic l...
34% of patients are asymptomatic at the time of presentation.
Hypercalcemia (28%): anorexia, abdominal pain, somnolence, polydipsia, polyuria, dehydration
Elevated creatinine (48%)
Anemi...
Treatment varies depending on level of disease activity and stage of MM.
Key determinant factor in choosing chemotherapy regimen is to establish if the patient is an autologous stem cell tran...
http://myeloma.org/Main.action
http://www.nccn.org/patients/guidelines/myeloma/
The 5-year survival rate is around 50%.
Median survival by R-ISS stage:
Stage I: has ...
C90.00 Multiple myeloma not having achieved remission
C90.01 Multiple myeloma in remission
C90.02 Multiple myeloma in relapse
203.00 Multiple myeloma, without mention of having achieved re...
MM is a plasma cell malignancy that causes end-organ damage.
Look for presence of “CRAB.”
Suspect MM if high total protein-to-albumin ratio is present.
Maintain high index of suspicion fo...
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