A chronic, systemic, infectious disease with any involvement of the CNS at any stage of syphilitic Treponema pallidum infection (primary, secondary, tertiary, and latent)
Transmitted ...
Many neurosyphilitic patients are asymptomatic...
T. pallidum cannot be grown in the laboratory, and there is no microbiologic test of cure.
Neurologic and CSF examination at 3 to 6 months and ev...
Berger JR, Dean D. Neurosyphilis. Handb Clin Neurol. 2014;121:1461–1472. [View Abstract on OvidMedline]
Chahine LM, Khoriaty RN, Tomford WJ, et al. The changing face of neurosy...
A52.3 Neurosyphilis, unspecified
A52.2 Asymptomatic neurosyphilis
A52.13 Late syphilitic meningitis
A52.11 Tabes dorsalis
A52.14 Late syphilitic encephalitis
A52.17 General paresis
A52.10 Symptom...
CNS involvement can occur at any stage of syphilis infection.
Procaine penicillin is the gold standard for treatment. Penicillin G benzathine does not reach detectable levels in the CSF...
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<bold>FIGURE 2-10.</bold> The illusion of depth when using scanning electron microscopy clearly reveals the corkscrew shape of cells of the syphilis-causing spirochete, <italic>Treponema pallidum</bold>.
<bold>FIGURE 2-10.</bold> The illusion of depth when using scanning electron microscopy clearly reveals the corkscrew shape of ...
<bold><italic>Figure 20-19</bold> Syphilitic aortitis in tertiary syphilis. A,</bold> The aortic root is dilated, so that the valve does not seal properly during diastole (regurgitation), and the valve leaflets are thickened because of chronic inflammation and scarring. <bold>B,</bold> Marked left ventricular dilation and hypertrophy caused by aortic regurgitation associated with dilation of aortic root.
<bold><italic>Figure 20-19</bold> Syphilitic aortitis in tertiary syphilis. A,</bold> The aortic root is dilated, s...