A rare hematologic disorder characterized by recurrent fevers, mouth ulcers, and infections attributable to regularly recurring severe neutropenia
Although inherited in an autosomal d...
Usually an infant (age <1 year)
Recurrent fevers, pharyngitis, gingivitis, stomatitis, and bacterial infections
Familial pattern in some cases (autosomal dominant)
Symptoms can range ...
Genetic counseling
Routine hospitalization not required
Regular and aggressive dental care
Antibacterial mouthwash Peridex is useful in decreasing gingivitis (5)[C].
Use clinical...
Blood counts should be obtained periodically to avoid overtreatment or ...
Dale DC. Cyclic and chronic neutropenia: an update on diagnosis and treatment. Clin Adv Hematol Oncol. 2011;9(11):868–869. [View Abstract on OvidMedline]
Haurie C, Dale DC, Mac...
Cyclic neutropenia is a benign disease; bowel necrosis and perforation are rare but may be associated with mortality.
Although establishing the diagnosis requires obtaining three blood ...
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