Skip to main content

Nocardiosis

John P. Barrett, MD, MPH, MS Reviewed 06/2018
 


BASICS

DESCRIPTION

  • A rare infectious disease caused by Nocardia spp. which are primarily located in ground and water sources

  • No pathognomonic presentation

  • Nocardiosis can be acute, subacute, or chronic, ...

DIAGNOSIS

HISTORY

  • Diagnosis requires a high index of clinical suspicion.

  • Symptoms vary by site of infection. Pulmonary, CNS, and cutaneous systems are most frequently infected:

    • Headache, anorexia, weight...

TREATMENT

GENERAL MEASURES

  • Consider infectious disease consultation.

  • Modify treatment based on sensitivity results.

MEDICATION

First Line

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Recovery after a variable period of convalescence; activity may be increased as patients improve. 

Patient Monitoring

Patients on high-dose sulfonamide therapy shou...

REFERENCES

1
Welsh O, Vera-Cabrera L, Salinas-Carmona MC. Current treatment for nocardia infections. Expert Opin Pharmacother.  2013;14(17):2387–2398. [View Abstract on OvidMedline]
2
Wilson JW. Noc...

ADDITIONAL READING

  • Bargehr J, Flors L, Leiva-Salinas C, et al. Nocardiosis in solid-organ transplant recipients: spectrum of imaging findings. Clin Radiol.  2013;68(5):e266–e271.

  • Burke VE, Lopez F...

CODES

ICD10

  • A43.9 Nocardiosis, unspecified

  • A43.0 Pulmonary nocardiosis

  • A43.1 Cutaneous nocardiosis

  • A43.8 Other forms of nocardiosis

ICD9

  • 039.9 Actinomycotic infection of unspecified site

  • 039.1 Pulmonary acti...

CLINICAL PEARLS

  • The diagnosis of nocardiosis requires a high degree of clinical suspicion.

  • Immunocompromised patients have more severe manifestations of disease.

  • Nocardiosis can progress and relapse des...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×