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Ovarian Cancer

Susan L. Zweizig, MD and Christina Kunycky, MD Reviewed 06/2020
 


BASICS

There are >22,000 new cases of ovarian cancer annually in the United States, and approximately 14,000 women will die of their disease; as such this the most lethal of gynecologic cancers, wh...

DIAGNOSIS

HISTORY

  • Acute presentation:

    • Shortness of breath (pleural effusion)

    • Nausea, vomiting, decreased oral intake (bowel obstruction)

    • Calf pain, shortness of breath (venous thromboembolism)

    • Severe abdom...

TREATMENT

GENERAL MEASURES

  • Surgical exploration with staging and debulking is critical. Optimal cytoreduction of tumor burden enhances effectiveness of adjuvant therapy and is associated with longer su...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Surgical patients should follow up within 2–4 weeks for post-operative assessment and then for further treatment planning. Patient undergoing chemotherapy should ...

REFERENCES

1
Beral V, Doll R, Hermon C, et al; and Collaborative Group on Epidemiological Studies of Ovarian Cancer. Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epi...

CODES

ICD10

  • C56.9 Malignant neoplasm of unspecified ovary

  • C56.1 Malignant neoplasm of right ovary

  • C56.2 Malignant neoplasm of left ovary

ICD9

183.0 Malignant neoplasm of ovary 

SNOMED

  • 93934004 Primary malign...

CLINICAL PEARLS

  • Family history of ovarian cancer or early-onset breast cancer is the most significant risk factor for the development of ovarian cancer, yet the vast majority of cases remain sporadic.

  • ...

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