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Ovarian Cancer

Susan Zweizig, MD and Aashna Saini, M.D. Reviewed 04/2024
 


BASICS

Ovarian cancer accounts for 4% of cancers occurring in women. According to the CDC, there are >19,000 new cases of ovarian cancer annually in the US, and approximately 14,000 deaths annually...

DIAGNOSIS

HISTORY

  • Vague, non-specific abdominal symptoms

  • Acute presentation:

    • Shortness of breath (pleural effusion)

    • Nausea, vomiting, decreased oral intake (bowel obstruction)

    • Calf pain, shortness of breat...

TREATMENT

Treatment determined by stage of disease 

GENERAL MEASURES

  • Surgical exploration with staging and debulking is critical. Optimal cytoreduction of tumor burden enhances effectiveness of adjuvant...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Surgical patients should follow-up within 4 weeks for post-operative assessment and for further treatment planning.

  • Patient undergoing chemotherapy should have reg...

REFERENCES

1
Beral  V, Doll  R, Hermon  C, et al; and Collaborative Group on Epidemiological Studies of Ovarian Cancer. Ovarian cancer and oral contraceptives: collaborative rea...

ADDITIONAL READING

Olsen CM, Green AC, Whiteman DC, et al. Obesity and the risk of epithelial ovarian cancer: A systematic review and meta-analysis. Eur J Cancer. 2007 Mar;43(4):6...

CODES

ICD10

  • C56.9 Malignant neoplasm of unspecified ovary

  • C56.1 Malignant neoplasm of right ovary

  • C56.2 Malignant neoplasm of left ovary

SNOMED

  • 93934004 Primary malignant neoplasm of ovary

  • 369529006 primary...

CLINICAL PEARLS

  • Family history of ovarian cancer or early-onset breast cancer is the most significant risk factor for the development of ovarian cancer, yet the vast majority of cases remain sporadic.

  • ...

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