An adult onset, progressive, neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra and other dopaminergic regions of the brain.
Cardinal symptoms i...
Diagnosis is based on clinical features (rest tremor, rigidity, bradykinesia, postural instability) and response to dopaminergic therapy.
PD is clinical diagnosis and gold standard for diagno...
PD treatment goal: Improve motor and nonm...
Avoid drug holidays is patient is having "off" time on levodopa.
Consider switching to dopamine agonist (non-ergot preferred), MAO-B inhibitors, or COMT inhibitors...
American Academy of Neurology practice parameter on initiation of treatment of PD: https://n.neurology.org/content/58/1/11.long
G21.11 Neuroleptic induced parkinsonism
G21.8 Other secondary parkinsonism
G21.4 Vascular parkinsonism
G21.19 Other drug induced secondary parkinsonism
G21 Secondary parkinsonism
G21.1 Other dru...
The classic description for PD is shaky (pill-rolling tremor at rest), stiff (cogwheel rigidity), slow (bradykinesia), and stumbling (shuffling gait).
No cure—goals are to delay disease...
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Clinical features of Parkinson's disease
Reprinted with permission from Rosdahl CB. Book of Basic Nursing. 7th ed. Philadelphia, PA: Lippincott-Raven; 1999:1063, Figure 77-3
Reprinted with permission from Rosdahl CB. Book of Basic Nursing. 7th ed. Philadelphia, PA: Lipp...
The clinical features of Parkinson disease.
Timby B.K., Smith N.E. [2003]. Introductory medical'surgical nursing [8th ed. p. 626]. Philadelphia: Lippincott Williams & Wilkins
Timby B.K., Smith N.E. [2003]. Introductory medical'surgical nursing [8th ed. p. 626]. Philad...