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Pemphigoid Gestationis

Tiffany A. Moore Simas, MEd, MPH, MD and Michelle D. Marieni, MD Reviewed 06/2021
 


BASICS

Uncommon pregnancy-associated autoimmune bullous dermatosis 

DESCRIPTION

  • Pemphigoid gestationis (PG) is a rare dermatopathic autoimmune-mediated, self-limited eruption most often occurring during...

DIAGNOSIS

HISTORY

  • Current pregnancy or recent delivery

  • Lesions begin as pruritic periumbilical papules that spread to trunk, back, buttocks, and arms.

  • Face, scalp, palms, soles, and mucous membranes usua...

TREATMENT

  • Goal is to reduce pruritic lesions and discomfort.

  • Treat mild disease with oral antihistamines and topical steroids.

  • Treat more involved cases primarily with systemic corticosteroids.

  • Severe ca...

ONGOING CARE

PATIENT EDUCATION

  • Benign disease; no permanent adverse sequelae (e.g., scarring) in the absence of secondary infection; usually resolves after delivery. Postinflammatory hyperpigmentation ...

REFERENCES

1
Santos-Alarcón  S, Benavente-Villegas  C, García-Briz  I, et al. Urticarial lesions in a pregnant woman. Acta Dermatovenerol Croat.  2018;26(1):71–72. [View Ab...

ADDITIONAL READING

  • Amber  KT, Murrell  DF, Schmidt  E, et al. Autoimmune subepidermal bullous diseases of the skin and mucosae: clinical features, diagnosis, and management....

SEE ALSO

Algorithm: Genital Ulcers 

CODES

ICD10

  • O26.40 Herpes gestationis, unspecified trimester

  • O26.42 Herpes gestationis, second trimester

  • O26.43 Herpes gestationis, third trimester

  • O26.41 Herpes gestationis, first trimester

SNOMED

  • 86081009...

CLINICAL PEARLS

  • Rare autoimmune bullous dermatosis of pregnancy and the puerperium

  • Originally named herpes gestationis on the basis of the morphologic herpetiform features. PG is not associated with he...

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