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Pemphigoid Gestationis

Kelsey Teresa Chabot, MD and Rachel C Taylor, MD Reviewed 05/2023
 


BASICS

Uncommon pregnancy-associated autoimmune bullous dermatosis 

DESCRIPTION

  • Pemphigoid gestationis (PG) is a rare, self-limited, autoimmune-mediated dermatopathic eruption of pregnancy. It most comm...

DIAGNOSIS

HISTORY

  • Current pregnancy or recent delivery

  • Intense pruritus preceding skin lesions

  • Initial lesions are pruritic periumbilical papules and annular plaques that spread to trunk, back, buttocks,...

TREATMENT

  • Goal is to reduce pruritic lesions and discomfort.

  • Treat mild disease with oral antihistamines and topical steroids.

  • Treat cases refractory to topical management with systemic corticosteroids.

  • ...

ONGOING CARE

PATIENT EDUCATION

  • Benign disease; no permanent adverse sequelae (e.g., scarring) in the absence of secondary infection; usually resolves after delivery. Postinflammatory hyperpigmentation ...

REFERENCES

1
Bolognia JL, Jorizzo JL, Rapini RP, et al., Dermatology. New York, NY: Mosby. 2003: 425-432.
2
Chi  CC, Wang  SH, Charles-Holmes  R, et al. Pemphigoid gestationis: ea...

ADDITIONAL READING

SEE ALSO

Algorithm: Genital Ulcers 

CODES

ICD10

  • O26.40 Herpes gestationis, unspecified trimester

  • O26.42 Herpes gestationis, second trimester

  • O26.43 Herpes gestationis, third trimester

  • O26.41 Herpes gestationis, first trimester

SNOMED

  • 86081009...

CLINICAL PEARLS

  • Rare autoimmune bullous dermatosis of pregnancy and the puerperium

  • Originally named herpes gestationis on the basis of the morphologic herpetiform features. PG is not associated with he...

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