Rare, potentially fatal autoimmune mucoc...
Multiple, painful, nonhealing ulcers in the mouth, commonly the buccal and labial mucosa, palate, and tongue (70%). Roughly 20% appears on genital mucosa. Rarely, erosions can appear ...
Minim...
Huang A, Madan RK, Levitt J. Future therapies for pemphigus vulgaris: rituximab and beyond. J Am Acad Dermatol. 2016;74(4):746–753. [View Abstract on OvidMedline]
Leshem YA, Gd...
49420001 Pemphigus vulgaris (disorder)
403630005 Drug-induced pemphigus vulgaris (disorder)
361212009 Oral pemphigus vulgaris (disorder)
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<bold><italic>Figure 14.78.</bold></bold> Pemphigus vulgaris. <bold>A.</bold> Bulla. <bold>B.</bold> Erosion.
<bold><italic>Figure 14.78.</bold></bold> Pemphigus vulgaris. <bold>A.</bold> Bulla. <bold>B....
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is unknown, binds to an antigen on the outer leaflet of the plasma membranes (desmosomes) of keratinocytes, especially in the basal regions. (figure continues)
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is u...
Pemphigus vulgaris. Suprabasal dyshesion leads to an intraepidermal blister containing acantholytic keratinocytes.
FIGURE 52.5 Pemphigus vulgaris blisters on the forearm.