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Pemphigus Vulgaris

 

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Figure 14.78. Pemphigus vulgaris. A. Bulla. B. Erosion.
Figure 14.78. Pemphigus vulgaris. A. Bulla. B. Erosion.
Figure 14.78. Pemphigus vulgaris. A. Bulla. B. Erosion.
Figure 14.78. Pemphigus vulgaris. A. Bulla. B. Erosion.
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is unknown, binds to an antigen on the outer leaflet of the plasma membranes (desmosomes) of keratinocytes, especially in the basal regions. (figure continues)
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is un...
Pemphigus vulgaris. Suprabasal dyshesion leads to an intraepidermal blister containing acantholytic keratinocytes.
Pemphigus vulgaris. Suprabasal dyshesion leads to an intraepidermal blister containing acantholytic keratinocytes.
FIGURE 52.5 Pemphigus vulgaris blisters on the forearm.
FIGURE 52.5 Pemphigus vulgaris blisters on the forearm.
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