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<bold><italic>Figure 14.78.</bold></bold> Pemphigus vulgaris. <bold>A.</bold> Bulla. <bold>B.</bold> Erosion.
<bold><italic>Figure 14.78.</bold></bold> Pemphigus vulgaris. <bold>A.</bold> Bulla. <bold>B....
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is unknown, binds to an antigen on the outer leaflet of the plasma membranes (desmosomes) of keratinocytes, especially in the basal regions. (figure continues)
A pathogenetic mechanism of suprabasal dyshesion in pemphigus vulgaris. (1) A circulating autoantibody, whose stimulus for production is u...
Pemphigus vulgaris. Suprabasal dyshesion leads to an intraepidermal blister containing acantholytic keratinocytes.
FIGURE 52.5 Pemphigus vulgaris blisters on the forearm.