Synonym(s): sore throat; tonsillitis; “strep throat”
Acute or chronic inflammation of the pharyngeal mucosa and underlying structures of the throat
Group A Streptococcus (GAS) pharyngi...
Sore throat
Difficulty swallowing (dysphagia) or pain on swallowing (odynophagia)
Cough (uncommon in GAS pharyngitis)
Hoarseness; “hot potato” voice
Fever
Anorexia
Chills
Malaise; fatigue
Hea...
Complete the full course of antibiotic therapy, regardless of symptom response.
Patients are generally noninfectious after 24 hours of antibiotics.
Follow-up cultur...
Herpes Simplex; Infectious Mononucleosis, Epstein-Barr Virus Infections; Rheumatic Fever
Algorithm: Pharyngitis
J31.1 Chronic nasopharyngitis
A54.5 Gonococcal pharyngitis
B08.5 Enteroviral vesicular pharyngitis
A56.4 Chlamydial infection of pharynx
J02.9 Acute pharyngitis, unspecified
J02 Acute pharyngiti...
Most cases of pharyngitis are viral and do not require antibiotics.
The risk associated with undiagnosed and untreated group A streptococcal infection is for rheumatic sequelae—a rare c...
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Eruption occurring in a young man who received amoxicillin just prior to mononucleosis diagnosis
Close-up of previous patient
<bold>Figure 40.11</bold> Tonsils of an adolescent who has infectious mononucleosis; note the red enlarged tonsils with the thick white covering.
<bold>Figure 40.11</bold> Tonsils of an adolescent who has infectious mononucleosis; note the red enlarged tonsils with the t...
Herpes simplex cervicitis.
<bold>FIG. 79.1.</bold> A: Mitral valve from a patient with mitral stenosis from rheumatic fever (viewed from atrium). Notice the thickened calcific leaflets and thickened chordae tendineae compared with a normal mitral valve (B). (Courtesy of W.D. Edwards, M.D., Mayo Clinic.)
<bold>FIG. 79.1.</bold> A: Mitral valve from a patient with mitral stenosis from rheumatic fever (viewed from atrium). Notice ...
<bold>FIG. 79.2.</bold> A: Erythema marginatum in an adult with rheumatic fever. B: Closer view of rash. (Courtesy of P. Witman, M.D., Mayo Clinic.)
<bold>FIG. 79.2.</bold> A: Erythema marginatum in an adult with rheumatic fever. B: Closer view of rash. (Courtesy of P. Witma...
FIG. 11.55. Pharyngitis in infectious mononucleosis. This girl has inflamed, bilaterally swollen tonsils with a diffuse exudate, as is often seen with infectious mononucleosis.
FIG. 11.55. Pharyngitis in infectious mononucleosis. This girl has inflamed, bilaterally swollen tonsils with a diffuse exudate, as is oft...
Figure 152.1. Radiographs of a previously healthy 51-year-old woman who presented with a 2-month history of fatigue and generalized weakness, with a 1-week history of worsening confusion, and a 24-hour history of aphasia and severe headache. <bold>A:</bold> T1-weighted magnetic resonance image demonstrates a 7.5-cm ring-enhancing lesion in the left frontal lobe with associated vasogenic edema and midline shift. <bold>B:</bold> T1-weighted sagittal view demonstrates a septated or loculated lesion. <b>C:...
Figure 152.1. Radiographs of a previously healthy 51-year-old woman who presented with a 2-month history of fatigue and generalized weakne...
<bold><italic>Figure 11-12</bold> The blood in infectious mononucleosis.</bold> The large "atypical" lymphocyte is characteristic.
<bold><italic>Figure 11-12</bold> The blood in infectious mononucleosis.</bold> The large "atypical" lymphocyte is...
Role of Epstein-Barr virus (EBV) in infectious mononucleosis, nasopharyngeal carcinoma, and Burkitt lymphoma. EBV invades and replicates within the salivary glands or pharyngeal epithelium, and is shed into the saliva and respiratory secretions. In some people, the virus transforms pharyngeal epithelial cells, leading to nasopharyngeal carcinoma. In people who are not immune from childhood exposure, EBV causes infectious mononucleosis. EBV infects B lymphocytes, which undergo polyclonal act...
Role of Epstein-Barr virus (EBV) in infectious mononucleosis, nasopharyngeal carcinoma, and Burkitt lymphoma. EBV invades and replicates w...
Herpes simplex: retroauricular
HSV - culture-confirmed. Painful vesicles on the foot.
Infectious Mononucleosis White cells Agranulocytosis Proliferation of lymphocytes (12-25 X 10 9 /L) Greater than 20% reactive lymphocytes Immunoblasts may be present Plasmacytoid lymphocytes may be present Red cells May have an autoimmune hemolytic anemia Platelets Normal to decreased Serological tests Paul-Bunnell heterophile antibodies positive Peripheral Smear
Infectious Mononucleosis White cells Agranulocytosis Proliferation of lymphocytes (12-25 X 10 9 /L) Greater than 20% reactive lymp...
infectious mononucleosis
<bold>FIGURE 20-50. Infectious mononucleosis.</bold> Atypical lymphocytes are characteristic.
Palatal petechiae strongly suggestive of sterptococcal pharyngitis
FIG. 6.2. Eczema herpeticum. Ulcers and excoriations, as in these two cases [patient 1 (A, B), patient 2 (C)], usually characterize the eruption, although vesicles may be seen at times (D). More severe cases [patient 3 (E), patient 4 (F, G), patient 5 (H)], with generalized eruptions, require intravenous therapy with acyclovir.
FIG. 6.2. Eczema herpeticum. Ulcers and excoriations, as in these two cases [patient 1 (A, B), patient 2 (C)], usually characterize the eru...
Herpes cervicitis.
Herpes simplex eruption on the waist of an RN - present for a few days
Tonsillar exudate. May be present in viral tonsillitis as well as group A strep infection.