Polyarteritis nodosa (PAN) is an antineutrophil cytoplasmic antibody (ANCA)-negative necrotizing arteritis of medium-sized muscular arteries and (occasionally) small arteries. Arteri...
There are no formal diagnostic criteria for PAN (1,2).
Suspect PAN with:
Acute, sometimes fulminant multisystem disease with a relatively short prodrome (i.e., weeks to months)
Vasculitic skin...
Severe (life-threatening) disease: corticosteroids (CS) (h...
CBC, urinalysis, renal and hepatic function tests.
Acute-phase reactants (e.g., ESR, CRP) may help monitor disease activity.
The revised 2009 Five...
M30.0 Polyarteritis nodosa
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
M30.8 Other conditions related to polyarteritis nodosa
M31.7 Microscopic polyangiitis
155441006 Polyar...
PAN is a necrotizing vasculitis of small- to medium-sized muscular arteries with lack of granuloma formation that spares veins and pulmonary arteries.
Clinical features of PAN depend on...
Sign up for a 10-day FREE Trial now and receive full access to all content.
Nodular, painful, hemorrhagic skin lesion in a patient with polyarteritis nodosa.
Areas of conjunctival edema and necrosis in polyarteritis nodosa.
Polyarteritis nodosa. The intense inflammatory cell infiltrate in the arterial wall and surrounding connective tissue is associated with fibrinoid necrosis and disruption of the vessel wall.
Polyarteritis nodosa. The intense inflammatory cell infiltrate in the arterial wall and surrounding connective tissue is associated with f...
Chronic hepatitis with cirrhosis. A photomicrograph of the liver from a patient with long-standing chronic active hepatitis B shows hepatocellular nodules and chronically inflamed fibrous septa.
Chronic hepatitis with cirrhosis. A photomicrograph of the liver from a patient with long-standing chronic active hepatitis B shows hepato...
<bold>Fig GU 7-2 Polyarteritis nodosa.</bold> An aortogram demonstrates innumerable small aneurysms arising from vessels throughout the abdomen. The aorta and its major branches are spared.
<bold>Fig GU 7-2 Polyarteritis nodosa.</bold> An aortogram demonstrates innumerable small aneurysms arising from vessels throu...