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Polycystic Ovarian Syndrome (PCOS)

Melissa Dennis, MD and Rachel Soffer Parritz, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Polycystic ovarian syndrome (PCOS) is a common endocrine disorder with heterogeneous manifestations that affects 6–10% of the U.S. population.

  • Hyperandrogenism, insulin resistance, an...

DIAGNOSIS

HISTORY

  • A comprehensive history, including a family history of diabetes and premature onset of cardiovascular disease, is important in the differential diagnosis.

  • Focus on the onset and durati...

TREATMENT

GENERAL MEASURES

Lifestyle changes including appropriate nutrition and exercise to decrease body weight by as little as 5% can restore ovulation and increase insulin sensitivity (4)[A]. Treat...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

6-month intervals to evaluate response to therapy and to monitor weight and medication side effects 

Patient Monitoring

  • Counsel patient about the risk of endometria...

REFERENCES

1
Azziz R, Carmina E, Dewailly D, et al; for Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society. The Androgen Excess and PCOS Society criter...

SEE ALSO

Algorithm: Amenorrhea, Secondary 

CODES

ICD10

  • E28.2 Polycystic ovarian syndrome

  • L68.0 Hirsutism

ICD9

  • 256.4 Polycystic ovaries

  • 704.1 Hirsutism

SNOMED

  • 69878008 Polycystic ovaries (disorder)

  • 66520009 Female hirsutism (disorder)

CLINICAL PEARLS

  • Based on Rotterdam criteria, PCOS is diagnosed based on 2 of 3 of: (i) oligo-ovulation, (ii) clinical or biochemical signs of hyperandrogenism, (iii) polyctic ovaries.

  • Polycystic ovarie...

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