Polycythemia vera (PV) is a myeloproliferative clonal stem cell disorder marked by increased production of red blood cells (erythrocytosis) with excessive erythroid, myeloid, and meg...
Patients may be asymptomatic or present with nonspecific complaints, including fatigue, malaise, weight loss, sweating, and subjective weakness.
Erythromelalgia (burning pain of feet/h...
Risk factors: Patients >60 years with history of thrombosis are high risk. Those who are <60 years with no history of thrombosis but with elevated platelets (>150,00...
Avoid high-sodium diet; can cause fluid retention
Avoid iron sup...
Passamonti F. How I treat polycythemia vera. Blood. 2012;120(2):275–284.
Tefferi A, Fonseca R. Selective serotonin reuptake inhibitors are effective in the treatment of polycyt...
D45 Polycythemia vera
238.4 Polycythemia vera
289.0 Polycythemia, secondary
109992005 Polycythemia vera (clinical)
127066000 Familial polycythemia vera
367328005 Secondary polycythemia...
Erythrocytosis: Hgb >16.5 g/dL in men, >16.0 g/dL in women
JAK2 mutations are an important component of myeloproliferative disorders.
Bone marrow biopsy can help in diagnosis showi...
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