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Prostate Cancer

Reviewed 06/2018
 


BASICS

DESCRIPTION

  • The prostate is a male reproductive organ that contributes seminal fluid to the ejaculate.

  • The prostate gland is about the size of a walnut, averaging 20 to 25 g in volume in an adult...

DIAGNOSIS

HISTORY

  • Inquire about family history of CaP, symptoms of bladder outlet obstruction, and other voiding symptoms.

  • Anorexia and weight loss, bone pain or neurologic deficits from spinal cord com...

TREATMENT

Treatment options include (5): 
  • Watchful waiting: monitoring with expectation to provide palliation with symptoms

  • Active surveillance: close monitoring of PSA, DRE, and repeat biopsy at regula...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

  • Prostatectomy: PSA and DRE are recommended at regular intervals. PSA threshold-defining biochemical recurrence is evolving; however, recent data suggest a cutoff ...

REFERENCES

1
National Cancer Institute: http://seer.cancer.gov.
2
Thompson IM, Goodman PJ, Tangen CM, et al. The influence of finasteride on the development of prostate cancer. N Engl J Med.  2003;3...

ADDITIONAL READING

  • D’Amico AV, Whittington R, Malkowicz SB, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically lo...

CODES

ICD10

C61 Malignant neoplasm of prostate 

ICD9

185 Malignant neoplasm of prostate 

SNOMED

  • 399068003 Malignant tumor of prostate (disorder)

  • 399490008 Adenocarcinoma of prostate

  • 254900004 Carcinoma of pr...

CLINICAL PEARLS

  • Prostate cancer is clinically diverse, ranging from low-risk/indolent disease to high-risk/aggressive disease.

  • Most men with CaP are asymptomatic.

  • The use of PSA for CaP screening is con...

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