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Prostate Cancer

Dylan Buller, MD and Joseph R Wagner, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • The prostate is a male reproductive gland that contributes seminal fluid to the ejaculate.

  • Prostate gland is approximately the size of a walnut, 20 to 25 g in an adult male; enlarges ...

DIAGNOSIS

HISTORY

Symptoms of bladder outlet obstruction, and other voiding symptoms. 

PHYSICAL EXAM

DRE to assess for prostatic masses, firmness, or asymmetry 

DIFFERENTIAL DIAGNOSIS

Benign prostatic hype...

TREATMENT

  • Use Prostate Predict Calculator to help patient consider treatment options: https://prostate.predict.nhs.uk/.

  • Treatment options include:

    • Watchful waiting: monitoring with expectation...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Prostatectomy: PSA and DRE;some combination of CT/MRI/PET/bone scan obtained at recurrence. If the PSA recurrence is due to local disease, salvage radiation +/- A...

REFERENCES

1
Grossman  DC, Curry  SJ, Owens  DK, et al; and US Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation st...

CODES

ICD10

  • C61 Malignant neoplasm of prostate

  • Z80.42 Family history of malignant neoplasm of prostate

  • D07.5 Carcinoma in situ of prostate

SNOMED

  • 399068003 Malignant tumor of prostate

  • 93974005 Primary malig...

CLINICAL PEARLS

  • Use of PSA for CaP screening is controversial; shared decision-making is recommended.

  • Care must be taken when interpreting PSA levels in patients taking 5-α-reductase inhibitors.

  • Decisio...

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