The G20210A is a gain of function mutation where adenine is substituted for a guanine at the 20210 noncoding position of the prothrombin (a.k.a. factor II) gene.
Prothrombin 20210 mut...
Previous VTE
Family history of VTE
Family history of prothrombin 20210 mutation
Unilateral swollen, erythematous, and tender calf is significant for a possible DVT.
Positive ...
Compression stockings for prevention
DVT prophylaxis as appropriate if patient admitted to hospital
Warfarin use requires periodic (weekly and the...
Kearon C, Akl EA. Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism. Blood. 2014;123(12):1794–1801. [View Abstract...
440989002 prothrombin G20210A mutation (disorder)
441421001 Heterozygous prothrombin G20210A mutation
441420000 Homozygous prothrombin G20210A mutation
Prothrombin 20210 mutation is the second most common inherited risk factor for VTE after factor V Leiden mutation.
Asymptomatic patients with prothrombin 20210 mutation do not need anti...
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<bold><italic>Figure 13.28.</bold></bold> Measurement of the lower extremity circumference. Increase in size is consistent with swelling, which might be due to a deep venous thrombosis.
<bold><italic>Figure 13.28.</bold></bold> Measurement of the lower extremity circumference. Increase in size is co...
Schematic of development of thrombus in deep vein
Figure 16-55 <bold>IVC UMBRELLA FILTER. A. AP Lumbar. B. Lateral Lumbar.</bold> This metallic umbrella fillter is placed in the inferior vena cava to capture emboli from the lower extremities in patients with thrombophlebitis.
Figure 16-55 <bold>IVC UMBRELLA FILTER. A. AP Lumbar. B. Lateral Lumbar.</bold> This metallic umbrella fillter is placed in th...
Figure 18-110<bold>DEEP VENOUS THROMBOSIS. A. Ultrasound,Lower Limb.</bold>Note the thrombus within the femoral vein (<italic>arrows</bold>). Failure of the vein to collapse from the compression of the ultra sound head confirms the presence of endoluminal thrombus (<italic>arrowheads</bold>). <bold>B. Pulmonary Embolism,Pulmonary CT Angiogram, Axial Chest.</bold>Observe the emboliin the pulmonary artery (<italic>arrow</bold>) and left atrium (<italic>arrow</bold>). <bold><italic>COMMENT:</bold></bold>Lower limb ultrasound evaluation is routinely p...
Figure 18-110<bold>DEEP VENOUS THROMBOSIS. A. Ultrasound,Lower Limb.</bold>Note the thrombus within the femoral vein (<ital...
<bold>FIGURE 24-15</bold> Common sites of venous thrombosis. (<bold>A</bold>) Superficial thrombophlebitis. (<bold>B</bold>) Most common form of deep thrombophlebitis. (<bold>C</bold> and <bold>D</bold>) Deep thrombophlebitis from the calf to iliac veins.
<bold>FIGURE 24-15</bold> Common sites of venous thrombosis. (<bold>A</bold>) Superficial thrombophlebitis. (<b...