Autoinflammatory disease triggered by calcium pyrophosphate dihydrate (CPPD) crystal deposition within joints
One of many diseases associated with pathologic deposition of crystal; mi...
Presentation often mimics gout (“pseudogout”).
Acute CPPD: pain and swelling of ≥1 or more joints; knee involved in 50% of cases; ankle, wrist, toe, and shoulder involvement are also c...
Rest and elevate affected joint(s).
Apply ice/cool compresses to affected joints.
Non–weight-bearing on affected joint while painfu...
Bruges-Armas J, Bettencourt BF, Couto AR, et al. Effectiveness and safety of infliximab in two cases of severe chondrocalcinosis: nine years of follow-up. Case Rep Rheumatol. ...
M11.20 Other chondrocalcinosis, unspecified site
M11.269 Other chondrocalcinosis, unspecified knee
M11.29 Other chondrocalcinosis, multiple sites
275.49 Other disorders of calcium metaboli...
Suspect CPPD in arthritis cases that do not follow a pattern typical of degenerative joint disease (e.g., metacarpophalangeal joints, wrists).
Perform arthrocentesis to confirm diagnosi...
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