Autoinflammatory disease triggered by calcium pyrophosphate dihydrate (CPPD) crystal deposition within joints
One of many diseases associated with pathologic deposition of crystal; mi...
Presentation often mimics gout (“pseudogout”).
Acute CPPD: pain and swelling of ≥1 or more joints; knee involved 50% of the time; ankle, wrist, toe, and shoulder are also common.
Proxim...
Rest and elevate affected joint(s).
Apply ice/cool compresses to affected joints.
Non–weight-bearing on affected joint while painfu...
Bruges-Armas J, Bettencourt BF, Couto AR, et al. Effectiveness and safety of infliximab in two cases of severe chondrocalcinosis: nine years of follow-up. Case Rep Rheumatol. ...
M11.20 Other chondrocalcinosis, unspecified site
M11.269 Other chondrocalcinosis, unspecified knee
M11.29 Other chondrocalcinosis, multiple sites
275.49 Other disorders of calcium metaboli...
Suspect CPPD in arthritis cases that do not follow a pattern typical of degenerative joint disease.
Perform arthrocentesis to confirm diagnosis.
If septic arthritis is suspected, treat e...
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Gout in Knee Labeled
Gouty (uric acid) tophi in a middle-aged woman with longstanding gout
<bold>FIG. 4.4.</bold> This "chalky" substance was aspirated from a patient's inflamed olecranon bursa, an appearance that is virtually diagnostic of tophaceous gout.
<bold>FIG. 4.4.</bold> This "chalky" substance was aspirated from a patient's inflamed olecranon bursa, an appearance that is ...
<bold>Fig B 10-17. Gout.</bold> Two examples of typical rat-bite erosions about the first metatarsophalangeal joint (arrows). The cystlike lesions have thin sclerotic margins and characteristic overhanging edges.
<bold>Fig B 10-17. Gout.</bold> Two examples of typical rat-bite erosions about the first metatarsophalangeal joint (arrows). ...
Chronic tophaceous gout involving the hands and wrists.
<bold>Fig B 10-18. Gout.</bold> Diffuse deposition of urate crystals in periarticular tissues of the hand produce multiple large, lumpy soft-tissue swellings representing gouty tophi. Note the erosive changes that typically involve the carpal bones and the distal interphalangeal and metacarpophalangeal joints of the fifth digits.
<bold>Fig B 10-18. Gout.</bold> Diffuse deposition of urate crystals in periarticular tissues of the hand produce multiple lar...
Figure 10-207 <bold>SKELETAL DISTRIBUTION OF GOUT.</bold>
Figure 10-210 <bold>GOUT: BONE EROSIONS. PA Foot.</bold> Observe the marginal erosion, demonstrating a classic overhanging margin sign (<italic>arrow</bold>), periarticular erosion (<italic>arrowhead</bold>), and intraosseous erosion (<italic>crossed arrow</bold>).
Figure 10-210 <bold>GOUT: BONE EROSIONS. PA Foot.</bold> Observe the marginal erosion, demonstrating a classic overhanging mar...