Skip to main content

Reactive Arthritis (Reiter Syndrome)

Douglas William MacPherson, MD, MSc(CTM), FRCPC Reviewed 06/2022
 


BASICS

Reiter syndrome is a seronegative, multisystem, inflammatory disorder classically involving joints, the eye, and the lower genitourinary (GU) tract, and skin. It is a post-infectious auto-immun...

DIAGNOSIS

  • Clinical presentation with joint, eye, and GU inflammation (“classic triad”) and negative serologic testing for rheumatoid factor

  • Classic symptoms not always present

  • HLA-B27 testing is not req...

TREATMENT

GENERAL MEASURES

Treatment is determined by symptoms. 
  • Conjunctivitis does not require specific treatment.

  • Iritis requires treatment.

  • Mucocutaneous lesions do not require treatment.

  • Physical ther...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Activity modification until joint inflammation subsides 

Patient Monitoring

Monitor clinical response to anti-inflammatory drugs. Observe for complications, particu...

REFERENCES

1
Schmitt SK. Reactive arthritis. Infect Dis Clin North Am. 2017;31(2):265-277.
2
Padhan P, Danda D. Clinical spectrum of post-streptococcal reactive arthritis (PSRA) revisited: Juvenile versu...

ADDITIONAL READING

  • Boring  MA, Hootman JM, Liu  Y, et al. Prevalence of arthritis and arthritis-attributable activity limitation by urban-rural county classification—United ...

SEE ALSO

Ankylosing Spondylitis; Arthritis, Psoriatic; Behçet Syndrome 

CODES

ICD10

  • M02.30 Reiter’s disease, unspecified site

  • M02.39 Reiter’s disease, multiple sites

SNOMED

  • 67224007 Reiter’s disease (disorder)

  • 415141001 Post-genitourinary infection Reiter's disease (disorder)

  • 4...

CLINICAL PEARLS

  • Diagnosis of reactive arthritis is based on the clinical presentation of the classic triad of joint, eye, and GU inflammation and negative serologic testing for rheumatoid factor (sign...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×