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Retinopathy of Prematurity

Richard W. Allinson, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Proliferative disorder of the retinal blood vessels in premature infants: The normal retinal vascularization occurs nasally at ~36 weeks' gestational age and temporally at ~40 weeks'...

DIAGNOSIS

PHYSICAL EXAM

  • Acute ROP classification

    • Location

      • Zone I: posterior retina within a 60-degree circle centered on the optic nerve

      • Zone II: extends from the edge of zone I to the nasal ora anteriorl...

TREATMENT

GENERAL MEASURES

  • The CRYO-ROP study demonstrated a favorable outcome for eyes treated at threshold versus control eyes. Threshold ROP is defined as zone I or II, stage 3 (≥5 contiguous or 8 t...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Close follow-up of patients with ROP is required.

  • Eyes with low-risk prethreshold type 2 ROP receive follow-up every 2 to 4 days for at least 2 w...

REFERENCES

1
Fierson WM. Screening examination of premature infants for retinopathy of prematurity. Pediatrics.  2013;131(1):189–195. [View Abstract on OvidMedline]
2
Kishore K, Macwan KS. Need for ...

CODES

ICD10

  • H35.109 Retinopathy of prematurity, unspecified, unspecified eye

  • H35.119 Retinopathy of prematurity, stage 0, unspecified eye

  • H35.129 Retinopathy of prematurity, stage 1, unspecified eye

  • H35.1...

CLINICAL PEARLS

  • Infants with birth weight <1,500 g or gestational age ≤30 weeks and selected infants with birth weight 1,500 to 2,000 g or gestational age >30 weeks with an unstable clinical cou...

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