Antibody-mediated destruction of red blood cells (RBCs) that bear Rh surface antigens in individuals who lack the antigens and have become isoimmunized (sensitized) to them
System(s) ...
Jaundice of newborn
Kernicterus signs/symptoms (choreoathetoid movements, gaze abnormalities, dental enamel dysplasia)
Fetal hydrops or fetal death in utero if severe (see “Erythr...
Depending on severity of involvement, treatment of fetus may include the following:
Intrauterine transfusion (3)[A]
Early delivery—typically no later than 37 to 38 weeks’ gest...
In most cases, outpatient ambulatory management is appropriate during the antepartum period.
Antibody titer measured monthly in isoimmunized wome...
Delaney M, Matthews DC. Hemolytic disease of the fetus and newborn: managing the mother, fetus, and newborn. Hematology Am Soc Hematol Educ Program. ...
Anemia, Autoimmune Hemolytic; Erythroblastosis Fetalis
Algorithm: Jaundice
P55.0 Rh isoimmunization of newborn
O36.0990 Maternal care for other rhesus isoimmunization, unspecified trimester, not applicable or unspecified
T80.40XA Rh incompat react due to tranfs of b...
If paternity is certain, determining that the father does not carry the Rh(D) blood group antigen eliminates the need to give RhIG prophylaxis during pregnancy or the need for special ...
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Immune Hemolytic Anemia White cells May be elevated due to an increased in neutrophils Counts may approach 30 X 10<sup>9</sup> /L Platelets Usually normal Red cells Hb and Hct decreased Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors Peripheral Smear
Immune Hemolytic Anemia White cells May be elevated due to an increased in neutrophils Counts may approach 30 X 10<sup>9</...