Rhabdomyosarcoma

Vincent L Shaw, Jr, CAQ-SM, MD Reviewed 06/2022

BASICS

DESCRIPTION

Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissue assumed to originate from the same pluripotent mesenchyme cell as striated skeletal muscle. It occurs mainly as primary mal...

DIAGNOSIS

HISTORY

Presents as a progressive non-tender palpable mass
When presents in the head/neck, patients report diplopia (due to ophthalmoplegia), recurrent sinusitis, or persistent nasal discharge...

TREATMENT

Encompasses surgical resection, radiation, chemotherapy. Patients should always be referred to a multidisciplinary team with expertise in oncology for definitive treatment.

SURGERY/OTHER PROCEDURES

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

All patients should follow up with their multidisciplinary team. This allows monitoring of treatment response, early detection of locoregional relapse, metastatic...

REFERENCES

PDQ Pediatric Treatment Editorial Board. Childhood Rhabdomyosarcoma Treatment (PDQ®): Health Professional Version. 2021 Sep 23. In: PDQ Cancer Information Summaries [Internet]. Bethesda (M...

CODES

ICD10

C49.9 Malignant neoplasm of connective and soft tissue, unsp
C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
C49.5 Malignant neoplasm of connective and soft tiss...

CLINICAL PEARLS

RMS is more common in children but can develop in adults, the latest having the highest mortality.
Genetic disorders and congenital syndromes are associated with a higher risk of develo...

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