Skip to main content

Rhabdomyosarcoma

Adrian DaSilva-DeAbreu, MD, Jose Luis Perez-Lara, MD and William Bracamonte-Baran, MD, PhD Reviewed 06/2018
 


BASICS

DESCRIPTION

Rhabdomyosarcoma (RMS) is a malignancy of primitive mesenchymal cells with myogenesis capacity, which are in skeletal muscle tissues. It occurs mainly as primary malignancy, but can ...

DIAGNOSIS

HISTORY

  • Presents as a progressive painless mass of the head and neck, genitourinary tissue, trunk, or extremities

  • RMS of genitourinary tissue may present as vaginal bleeding in females.

  • Other s...

TREATMENT

The three tenets of treatment for adults and children are composed of surgical resection, radiation therapy, and chemotherapy. Patients should be referred to a multidisciplinary team with ex...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

All patients should follow up with their multidisciplinary treatment team, a necessary practice for treatment response, early detection of locoregional relapse, m...

REFERENCES

1
National Cancer Institute. Childhood rhabdomyosarcoma treatment (PDQ®)–health professional version. https://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq. Upda...

ADDITIONAL READING

The references 1 and 4 are excellent additional resources. 

CODES

ICD10

  • C49.9 Malignant neoplasm of connective and soft tissue, unsp

  • C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck

  • C49.5 Malignant neoplasm of connective and soft tiss...

CLINICAL PEARLS

  • RMS are more common in children but can develop in adults.

  • Epidemiology and prognosis of each subtype of RMS can vary significantly.

  • Several genetic disorders and congenital syndromes ar...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×