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Rocky Mountain Spotted Fever

Lisa C Martinez, MD and Michael Mamone, Medical Degree Reviewed 04/2024
 


BASICS

Tickborne rickettsial diseases include spotted fever rickettsiosis (SFR), ehrlichiosis, and anaplasmosis. In the US, Rocky Mountain spotted fever (RMSF) is the SFR associated with the most seve...

DIAGNOSIS

  • Maintain high incidence of suspicion for Rickettsial infections when patients present with "influenza-like" symptoms during summer months regardless of a known history of tick exposure  (2)[...

TREATMENT

MEDICATION

First Line

Doxycycline is the treatment of choice in both adults and children (1)[A],(2)[C]. 
  • Untreated rickettsial infections have a high rate of morbidity and mortality (20-30% wi...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Patients with mild disease may be treated as outpatients if close follow-up is available.

  • Hospitalize patients with moderate to severe disease.

  • Infection does not c...

REFERENCES

1
Biggs  HM, Behravesh  CB, Bradley  KK, et al. Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever and other spotted fever group...

CODES

ICD10

A77.0 Spotted fever due to Rickettsia rickettsii 

SNOMED

  • 186772009 Rocky Mountain spotted fever (disorder)

  • 240616003 Eastern Rocky Mountain spotted fever

  • 240615004 Western Rocky Mountain spotte...

CLINICAL PEARLS

  • Diagnosis of RMSF requires a high index of clinical suspicion.

  • Tick bites are often unnoticed, and some patients may never develop a rash.

  • Begin treatment immediately without waiting for...

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