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Sarcoidosis

Donnah Mathews, FACP, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Sarcoidosis is a noninfectious, multisystem, granulomatous disease of unknown cause

    • Frequently presents with bilateral hilar adenopathy, pulmonary infiltrates, ocular or skin lesions.

    • ...

DIAGNOSIS

Diagnosis is based on three criteria: clinical presentation, nonnecrotizing granulomatous inflammation in tissue samples (although not always required), and exclusion of other diagnoses. 

HISTORY

TREATMENT

  • Many patients undergo spontaneous remission.

  • No treatment may be necessary in asymptomatic individuals, but treatment may be required for cardiac, CNS, renal, or ocular involvement.

  • No treatme...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Approximately 23% of patients with sarcoidosis will develop a new disease manifestation within 3 years of baseline evaluation.

  • Monitor serum calc...

REFERENCES

1
Dumas  O, Abramovitz  L, Wiley  AS, et al. Epidemiology of sarcoidosis in a prospective cohort study of U.S. women. Ann Am Thorac Soc.  2016;13(1):67–71. [View...

CODES

ICD10

  • D86.89 Sarcoidosis of other sites

  • D86.81 Sarcoid meningitis

  • D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes

  • D86.8 Sarcoidosis of other sites

  • D86.87 Sarcoid myositis

  • D86.0 Sarcoidosis o...

CLINICAL PEARLS

  • Sarcoidosis is a noninfectious, multisystem, granulomatous disease of unknown cause, typically affecting young and middle-aged adults.

  • Diagnosis is based on clinical findings, exclusion...

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