Schizophrenia

Anna Loyal Jackson, MD and Jeffrey Stovall, MD Reviewed 06/2018

BASICS

Schizophrenia is a persistent and severe psychiatric condition characterized by neurocognitive decline and impairment in reality testing.

DESCRIPTION

Major psychiatric disorder characterized by ...

DIAGNOSIS

Focus on identifying an insidious social and functional decline per history with the onset of ≥2 of the following characteristic symptoms on mental status exam:

Delusions (fixed, false belie...

TREATMENT

MEDICATION

First Line

Two classes of antipsychotic medications: typical and atypical. First-line treatment is with an atypical antipsychotic given lower potential for extrapyramidal side effec...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Long-term symptom management and rehabilitation depend on engagement in ongoing pharmacologic and psychosocial treatment.
Monitoring is based on evaluation of symp...

REFERENCES

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Association; 2013.

Hasan A, Falkai P, Wobrock T, et al;...

ADDITIONAL READING

Saks E. The Center Cannot Hold: My Journey Through Madness. New York, NY: Hyperion; 2007.

CODES

ICD10

F20.9 Schizophrenia, unspecified
F20.0 Paranoid schizophrenia
F20.1 Disorganized schizophrenia
F20.2 Catatonic schizophrenia
F20.5 Residual schizophrenia
F20.3 Undifferentiated schizophrenia
F20....

CLINICAL PEARLS

A debilitating chronic mental illness that affects all cultures
Schizophrenia is characterized by positive symptoms, including hallucinations, delusions, and negative symptoms, includin...

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