Schizophrenia

Lauren Elizabeth Kwan, Doctor of Medicine and Jeffrey Stovall, MD Reviewed 06/2022

BASICS

A severe and persistent mental illness characterized by delusions, hallucinations, disorganization of thought and behavior, cognitive dysfunction, and impairment in reality testing

DESCRIPTION

M...

DIAGNOSIS

Focus on identifying an insidious social and functional decline over a ≥ 6-month period (differentiates schizophrenia from brief psychotic and schizophreniform disorders). At least 2 of the ...

TREATMENT

MEDICATION

First Line

Two classes of antipsychotic medications: typical and atypical. First-line treatment is with an atypical antipsychotic given lower potential for extrapyramidal side effec...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Long-term symptom management and rehabilitation depend on engagement in ongoing pharmacologic and psychosocial treatment.
Monitoring is based on evaluation of symp...

REFERENCES

Murrie B, Lappin J, Large M. Transition of substance-induced, brief, and atypical psychoses to schizophrenia: a systematic review and meta-analysis. Schizophrenia Bulletin. 2020;46(3):505-...

CODES

ICD10

F20.3 Undifferentiated schizophrenia
F20.5 Residual schizophrenia
F20.2 Catatonic schizophrenia
F20.81 Schizophreniform disorder
F20.9 Schizophrenia, unspecified
F20.1 Disorganized schizophrenia
...

CLINICAL PEARLS

Schizophrenia is a severe and persistent mental illness that impacts cognition and functioning and requires a multidisciplinary team approach to assist with coping, treatment, and to p...

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