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Schizophrenia

Lauren Elizabeth Kwan, Doctor of Medicine and Jeffrey Stovall, MD Reviewed 06/2022
 


BASICS

A severe and persistent mental illness characterized by delusions, hallucinations, disorganization of thought and behavior, cognitive dysfunction, and impairment in reality testing 

DESCRIPTION

  • M...

DIAGNOSIS

Focus on identifying an insidious social and functional decline over a ≥ 6-month period (differentiates schizophrenia from brief psychotic and schizophreniform disorders). At least 2 of the ...

TREATMENT

MEDICATION

First Line

  • Two classes of antipsychotic medications: typical and atypical. First-line treatment is with an atypical antipsychotic given lower potential for extrapyramidal side effec...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Long-term symptom management and rehabilitation depend on engagement in ongoing pharmacologic and psychosocial treatment.

  • Monitoring is based on evaluation of symp...

REFERENCES

1
Murrie B, Lappin J, Large M. Transition of substance-induced, brief, and atypical psychoses to schizophrenia: a systematic review and meta-analysis. Schizophrenia Bulletin. 2020;46(3):505-...

SEE ALSO

Algorithm: Delirium 

CODES

ICD10

  • F20.3 Undifferentiated schizophrenia

  • F20.5 Residual schizophrenia

  • F20.2 Catatonic schizophrenia

  • F20.81 Schizophreniform disorder

  • F20.9 Schizophrenia, unspecified

  • F20.1 Disorganized schizophrenia

  • ...

CLINICAL PEARLS

  • Schizophrenia is a severe and persistent mental illness that impacts cognition and functioning and requires a multidisciplinary team approach to assist with coping, treatment, and to p...

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