Sepsis

Afsha Rais Kaisani, FAAFP, MD, Nur-Alhuda Shahub, DO and Drew McBrayer, MD Reviewed 05/2023

BASICS

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) define the currently recognized terminology.

Sepsis: life-threatening acute organ dysfunction cau...

A thorough history, including medical, surgical, social, occupational, and travel to identify risk factors and potential sources.

Systems with specific symptoms:

First airway/respiratory stabilization, then sepsis bundle: fluid resuscitation and antibiotics.

Targets to measure clinical response are:

Post-discharge follow-up with a primary care physician to review physical, cognitive and emotional problems related to sepsis.

Evans L, Rhodes A, Alhazzani W,

et al.

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med

. 2021;47:

1181–1247. doi:10.1...

Cecconi M, Evans L, Levy M, et al. Sepsis and septic shock. Lancet. 2018 Jul 7;392(10141):75-87.
Ferreira LD, McCants D, Velamuri S. Using m...

Early identification of patients with sepsis is imperative. qSOFA and SIRS scores are useful but imperfect aids in initial patient assessment. SOFA score is useful as a predictor of mo...

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