A potentially life-threatening drug-induced syndrome that results from synaptic increase in serotonin (5-hydroxytryptamine [5-HT]) concentrations and stimulation of peripheral and ce...
Serotonin syndrome is a clinical diagnosis.
Hunter Toxicity Criteria Decision Rules (3) aid in the diagnosis of clinically significant serotonin toxicity (sensitivity, 84%; specificity, 97%)....
Discontinuation of all serotonergic agents is primary management regardless of severity.
Supportive care is the mainstay of therapy. This includes administration of oxygen and aggressive IV f...
In mild cases of serotonin toxicity, address risks and benefits of restarting offending agents. Serotonergic medications need to be titrated slowly, and patients ...
Sign up for a 10-day FREE Trial now and receive full access to all content.