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Sjögren Syndrome

Mariya Milko, DO, MS Reviewed 06/2019
 


BASICS

  • Chronic inflammatory disorder characterized by lymphocytic infiltrates in exocrine organs

  • Typically presents with diminished salivary and lacrimal gland function, resulting in sicca symptoms suc...

DIAGNOSIS

  • 2016 ACR/EULAR classification criteria (2)[A]:

    • Based on five objective tests/items

    • Inclusion criteria applicable if the patient is positive for one ocular/oral dryness symptom based on the AEC...

TREATMENT

  • Treatment is primarily supportive.

  • Treat sicca symptoms—dry eyes, dry mouth.

  • Avoid medications that may worsen oral dryness (i.e., anticholinergics).

  • Promote good oral hygiene.

  • Treat systemic ma...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Frequency of follow-up depends on severity. 

Patient Monitoring

  • Monitor for complications, systemic manifestations, and relief of symptoms.

  • Medicolegal pitfalls: Mon...

REFERENCES

1
Mays JW, Sarmadi M, Moutsopoulos NM. Oral manifestations of systemic autoimmune and inflammatory diseases: diagnosis and clinical management. J Evid Based Dent Pract.  2012;12(Suppl 3...

CODES

ICD10

  • M35.00 Sicca syndrome, unspecified

  • M35.02 Sicca syndrome with lung involvement

  • M35.09 Sicca syndrome with other organ involvement

  • M35.03 Sicca syndrome with myopathy

  • M35.04 Sicca syndrome with ...

CLINICAL PEARLS

  • Many symptoms of SS can be treated with simple interventions such as artificial tears and sugar-free lozenges.

  • Consider lacrimal duct plugs for dry eyes.

  • Consider SS in patients with une...

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