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Sjögren Syndrome

Julie A Creech, DO, CAQSM and Alexander Vavra, Doctor of Osteopathy Reviewed 05/2023
 


BASICS

  • First described by Swedish ophthalmologist Henrik Sjögren. Chronic autoimmune disorder characterized by inflammation from lymphocytic infiltration of exocrine organs (especially lacrimal and sa...

DIAGNOSIS

  • 2016 ACR/EULAR classification criteria (1)[A]:

    • Based on five objective tests/items

    • Inclusion criteria applicable if the patient is positive for one ocular/oral dryness symptom (based on the A...

TREATMENT

  • Goals of treatment: symptom palliation, improved quality of life, monitor and treat systemic manifestations.

  • Prior to treatment of oral dryness assess baseline salivary gland function. Avoid ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Frequency of follow-up depends on severity. 

Patient Monitoring

Monitor for complications, systemic manifestations, and relief of symptoms. Medicolegal pitfalls: Mo...

REFERENCES

1
Shiboski  CH, Shiboski  SC, Seror  R, et al; and International Sjögren’s Syndrome Criteria Working Group. 2016 American College of Rheumatology/European League Agai...

CODES

ICD10

  • M35.01 Sjögren syndrome with keratoconjunctivitis

  • M35.03 Sjögren syndrome with myopathy

  • M35.00 Sjögren syndrome, unspecified

  • M35.0 Sjögren syndrome

  • M35.02 Sjögren syndrome with lung involvement

  • ...

CLINICAL PEARLS

  • Many symptoms of SS can be treated with nonpharmacologic interventions such as artificial tears and sugar-free candy/lozenges.

  • Coordinate care management with rheumatology, ophthalmolog...

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