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Staphylococcal Toxic Shock Syndrome

Reviewed 06/2018
 


BASICS

DESCRIPTION

  • An acute toxin-mediated illness associated with Staphylococcus aureus infection

  • Toxic shock syndrome (TSS) is characterized by sudden onset of high fever and rash with subsequent hypo...

DIAGNOSIS

HISTORY

  • Prodrome of 1 to 3 days that often includes malaise, myalgias, fever, chills, vomiting, and/or diarrhea

  • History of recent wound infection

  • Acute-onset fever and chills

  • Light-headedness or...

TREATMENT

Inpatient; typically requires admission to intensive care unit for close monitoring 

GENERAL MEASURES

  • Fluid resuscitation

  • Remove tampon or other vaginal foreign bodies.

  • Remove nasal packing if s...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Avoid continuous tampon use during menstruation.

  • Wound care/hygiene

DIET

As tolerated 

PROGNOSIS

  • Mortality: 4–22%; higher in older patients, nonmenstrual TSS, and if d...

REFERENCES

1
Walden A, Harriet H, Alyaqoobi M. Methicillin-resistant Staphylococcus aureus toxic shock syndrome. J Infect.  2008;56(2):161–162. [View Abstract on OvidMedline]
2
Centers for Disease C...

SEE ALSO

Measles (Rubeola); Pancreatitis, Acute; Rocky Mountain Spotted Fever; Scarlet Fever 

CODES

ICD10

  • A48.3 Toxic shock syndrome

  • B95.62 Methicillin resis staph infct causing diseases classd elswhr

ICD9

  • 040.82 Toxic shock syndrome

  • 041.12 Methicillin resistant Staphylococcus aureus in conditions ...

CLINICAL PEARLS

  • TSS is a rare, acute, toxin-mediated illness most commonly associated with S. aureus.

  • In women, TSS is traditionally associated with the continuous use of superabsorbent tampons during ...

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