Pigmented villonodular synovitis (PVNS), also known as tenosynovial giant cell tumor (TGCT), is a benign proliferative inflammatory disease associated with synovial hypervascularity....
Knee joints are most commonly affected, followed by the foot. Previously, data suggested the hip was more common than the foot, but that does not seem to be the case. Involvement of t...
Surgical resection (3,4,5)[A]
First-line treatment
Complete synovectomy by open surgical procedure for DPVNS.
Arthroscopic partial synovectomy for LPVNS
Patients with large popl...
Patients with recurrent disease usually present with more extensive involvement leading to redu...
Al-Nakshabandi NA, Ryan AG, Choudur H, et al. Pigmented villonodular synovitis. Clin Radiol. 2004;59(5):414–420. [View Abstract on OvidMedline] ...
M12.20 Villonodular synovitis (pigmented), unspecified site
M12.259 Villonodular synovitis (pigmented), unspecified hip
M12.269 Villonodular synovitis (pigmented), unspecified knee
M12.279 Vil...
PVNS is characterized by synovial inflammation and hemosiderin deposition with unknown etiology. However, it has been linked to trauma with subsequent joint hemorrhage.
There are two ty...
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