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Tardive Dyskinesia

Ying Tang, DO and Marilyn L Hines, DO Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Tardive dyskinesia (TD) is a neurologic condition resulting in delayed, persistent, abnormal, and involuntary stereotypic movements of the tongue, lips, face, trunk, and extremities ...

DIAGNOSIS

  • The diagnosis of TD is clinical and based on exclusion of other conditions of motor dysfunctions.

  • There is no biomarker or blood test for TD

  • According to the DSM-V, TD consists of involuntary ...

TREATMENT

MEDICATION

First Line

  • Discontinuation of dopamine receptor-blocking agent should be the initial option in patient who can tolerate such withdrawal, if possible. Many medications need to taper ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Warn patients that TD may be exacerbated by stimulant use (Ritalin, Adderall), neuroleptic withdrawal, and anticholinergics. Symptoms are affect...

REFERENCES

1
Strassnig  M, Rosenfeld  A, Harvey  PD. Tardive dyskinesia: motor system impairments, cognition and everyday functioning [published online ahead of print September ...

ADDITIONAL READING

  • Atlas  SJ, Agboola  F, Curfman  G. Effectiveness and value of 2 novel treatments for tardive dyskinesia. JAMA Intern Med.  2018;178(8):1110–1112. [Vi...

CODES

ICD10

  • G24.01 Drug induced subacute dyskinesia

SNOMED

  • 102449007 Tardive dyskinesia

  • 38941006 Neuroleptic-induced tardive dyskinesia

CLINICAL PEARLS

  • The older the patient and/or the longer the duration of antipsychotic use, the higher the risk of TD.

  • Use the minimum effective dosage and duration of antipsychotic medications that are...

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