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Tardive Dyskinesia

Chetna Dengri, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Tardive dyskinesia (TD) is a neurologic condition resulting in delayed, persistent, abnormal, and involuntary stereotypic movements of the tongue, lips, face, trunk, and extremities.

  • ...

DIAGNOSIS

  • The diagnosis of TD is clinical and based on exclusion of other conditions of motor dysfunctions.

  • According to the DSM-V, TD consists of involuntary athetoid or choreiform movements generally...

TREATMENT

MEDICATION

First Line

  • Discontinuation of dopamine receptor-blocking agent should be the initial option if possible. Many medications need to taper over weeks or months, during which TD symptom...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Warn patients that TD may be exacerbated by stimulant use (Ritalin, Adderall), neuroleptic withdrawal, and anticholinergics. Symptoms are affect...

REFERENCES

1
Karas H, Guduk M, Saatcioglu O. Withdrawal-emergent syskinesia and supersensitivity psychosis due to olanzapine use. Noro Psikiyatr Ars. 2016;53(2):178–180. doi:10.5152/npa.2015.10122
2
Bras...

CODES

ICD10

  • G24.01 Drug induced subacute dyskinesia

SNOMED

  • 102449007 Tardive dyskinesia

  • 38941006 Neuroleptic-induced tardive dyskinesia

CLINICAL PEARLS

  • The older the patient and/or the longer the duration of antipsychotic use, the higher the risk of TD.

  • Use the minimum effective dosage and duration of antipsychotic medications that are...

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