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Testicular Malignancies

Gabriel Neal, MA, MD and Jennifer L. Davis, MPH, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • Testicular cancer accounts for <1% of all cancers in men; it is the most common solid malignancy in men aged 15 to 40 years (1).

  • Rates for new cases have been rising 0.8% each yea...

DIAGNOSIS

HISTORY

  • A painless solid testicular mass is pathognomonic for testicular cancer. Other presentations include a painful testicular mass, testicular firmness, or scrotal/perianal heaviness.

  • Clin...

TREATMENT

GENERAL MEASURES

  • Nonseminoma: Includes mixed seminoma/nonseminoma tumors and seminoma histology with elevated AFP. See consensus guidelines.

    • Stage IA, IB, Stage IS, Stage IIA, Stage IIB, Stage...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

No single follow-up plan is appropriate for all patients and should be modified for the individual patient based on sites of disease, biology of...

REFERENCES

1
McHugh DJ, Gleeson JP, Feldman Dr. Testicular cancer in 2023: Current status and recent progress. CA Cancer J Clin. 2023. doi: 10.3322/caac.21819.
2
Siegel RL, Miller KD, Wagle NS, et al. C...

CLINICAL PEARLS

  • Testicular cancer is the most common solid organ tumor in men aged 1 to 40 years.

  • Testicular US is the initial imaging of choice for testicular pathology.

  • Radical inguinal orchiectomy is...

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