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Testosterone Deficiency

Michael Lao, MD and Stanton C. Honig, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Testosterone (T) is a critical anabolic hormone.

  • It is the principle circulating androgen in males.

  • Critical in cardiovascular, reproductive, and metabolic systems

  • Testosterone deficien...

DIAGNOSIS

HISTORY

  • Congenital and developmental abnormalities

  • Infertility, loss of libido, erectile dysfunction

  • Depression, fatigue, difficulty with concentration

  • Decreased muscle strength, energy level

  • Inc...

TREATMENT

Testosterone therapy (TT) has been shown to effectively ameliorate many symptoms of TD. TT is recommended for symptomatic men (e.g., low libido and/or erectile dysfunction, low energy level,...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Necessary to monitor effectiveness of therapy as well as for adverse effects: initially 3 to 6 months after treatment initiation and then annual...

REFERENCES

1
Paduch DA, Brannigan RE, Fuchs EF, et al. The laboratory diagnosis of testosterone deficiency. Urology.  2014;83(5):980–988. [View Abstract on OvidMedline]
2
Mulhall JP, Trost LW, Brann...

ADDITIONAL READING

  • Buvat J, Maggi M, Guay A, et al. Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment. J Sex Med.  2013;10(1):245–284...

CODES

ICD10

  • E29.1 Testicular hypofunction

  • E89.5 Postprocedural testicular hypofunction

ICD9

  • 257.2 Other testicular hypofunction

  • 257.1 Postablative testicular hypofunction

SNOMED

  • 111551000 Testicular hypofunc...

CLINICAL PEARLS

  • TD is common, and prevalence increases with age.

  • TD can have negative adverse impact on many bodily systems.

  • Symptomatic men with sexual dysfunction, obesity, unexplained anemia, bone de...

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