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Testosterone Deficiency

Michael Lao, MD, Gregory Murphy, MD and Stanton C. Honig, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Testosterone (T) is a critical anabolic hormone involved in various key metabolic pathways.

  • It is the principle circulating androgen in males.

  • Critical in bodily processes of the cardi...

DIAGNOSIS

HISTORY

Check for 
  • Congenital and developmental abnormalities

  • Infertility, loss of libido, erectile dysfunction (2)[A]

  • Depression, fatigue, difficulty with concentration

  • Decreased muscle strength...

TREATMENT

Testosterone replacement therapy (TRT) has been shown to effectively ameliorate many symptoms of TD. TRT is recommended for symptomatic men (e.g., low libido and/or erectile dysfunction, low...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Necessary to monitor effectiveness of therapy as well as for adverse effects: initially 3 to 6 months after treatment initiation and then annual...

REFERENCES

1
Roy CN, Snyder PJ, Stephens-Shields AJ, et al. Association of testosterone levels with anemia in older men: a controlled clinical trial. JAMA Intern Med.  2017;177(4):480–490. [View ...

ADDITIONAL READING

  • Buvat J, Maggi M, Guay A, et al. Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment. J Sex Med.  2013;10(1):245–284...

CODES

ICD10

  • E29.1 Testicular hypofunction

  • E89.5 Postprocedural testicular hypofunction

ICD9

  • 257.2 Other testicular hypofunction

  • 257.1 Postablative testicular hypofunction

SNOMED

  • 111551000 Testicular hypofunc...

CLINICAL PEARLS

  • T deficiency is common and prevalence increases with age.

  • T deficiency can have negative adverse impact on many bodily systems.

  • Symptomatic men with sexual dysfunction, obesity, and meta...

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