An acute syndrome of microangiopathic hemolytic anemia (MAHA) and consumptive thrombocytopenia with deposition of hyaline thrombi in terminal arterioles and capillaries leading to is...
Most common symptoms are nonspecific: nausea, vomiting, weakness, abdominal pain, fatigue, fever.
Related to thrombocytopenia
Easy bruising, purpura, or petechiae
Epistaxis, menorrhagia, blee...
Prompt treatment of TTP is necessary due to the high mortality (90%).
In the absence of another apparent cause, the dyad of MAHA and thrombocytopenia is sufficient to begin treatment for...
No maintenance therapy is required. After PEX is discontinued, blood counts should be monitored over a few months. If testing results remain normal, testing inter...
M31.1 Thrombotic microangiopathy
D69.42 Congenital and hereditary thrombocytopenia purpura
D69.3 Immune thrombocytopenic purpura
446.6 Thrombotic microangiopathy
287.33 Congenital and hered...
The diagnosis of TTP is made clinically; common symptoms are nonspecific: nausea; vomiting; weakness; abdominal pain; fatigue; fever; and easy bruising, purpura, or petechiae.
The histo...
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