An acute syndrome of microangiopathic hemolytic anemia (MAHA) and consumptive thrombocytopenia with deposition of hyaline thrombi in terminal arterioles and capillaries leading to is...
Most common symptoms are nonspecific: nausea, vomiting, weakness, abdominal pain, fatigue, fever.
Related to thrombocytopenia
Easy bruising, purpura, or petechiae
Epistaxis, menorrhagia, bleedi...
Prompt treatment of TTP is necessary due to the high mortality (90%).
Complete response to treatment is defined by a platelet count >150 × 109/L for 2 consecutive days, together with ...
Maintenance therapy is not required. After PEX is discontinued, blood counts should be monitored for months. If results remain normal, testing interval can be len...
M31.1 Thrombotic microangiopathy
D69.42 Congenital and hereditary thrombocytopenia purpura
D69.3 Immune thrombocytopenic purpura
446.6 Thrombotic microangiopathy
287.33 Congenital and hered...
The diagnosis of TTP is made clinically; common symptoms are nonspecific: nausea; vomiting; weakness; abdominal pain; fatigue; fever; and easy bruising, purpura, or petechiae.
The histo...
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