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Torch Infections

S. David Shahbodaghi, MD, MPH, CTropMed and Mary Lewis Black, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • An acronym describing a group of infections that are either acquired prenatally or during the process of birth and possess similar physical features, including skin and ocular manife...

DIAGNOSIS

HISTORY

  • Toxoplasmosis: Acute infection of mother is usually asymptomatic.

  • Syphilis: painless papule at the site of inoculation followed by regional lymphadenopathy

  • Rubella and CMV: maternal his...

TREATMENT

GENERAL MEASURES

  • Nutritional and respiratory support

  • Phototherapy for hyperbilirubinemia

MEDICATION

First Line

  • Toxoplasmosis: pyrimethamine (1 mg/kg/day PO daily for 6 months and then Monday, Wed...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Continue to follow neurologic and developmental status.

  • Toxoplasmosis: Follow up every 2 weeks until stable and then monthly while being treated;...

REFERENCES

1
Workowski KA, Berman S; for Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep.  2010;59(RR-12):1–110. [View Abstrac...

ADDITIONAL READING

  • Anzivino E, Fioriti D, Mischitelli M, et al. Herpes simplex virus infection in pregnancy and in neonate: status of art of epidemiology, diagnosis, therapy and prevention. Virol J. ...

CODES

ICD10

  • P00.2 Newborn affected by maternal infection/parasitic diseases

  • P37.1 Congenital toxoplasmosis

  • P35.1 Congenital cytomegalovirus infection

  • P35.2 Congenital herpesviral [herpes simplex] infectio...

CLINICAL PEARLS

  • Ensuring patients receive adequate prenatal care is paramount for prevention of TORCH infections.

  • TORCH infections may present similarly; targeted diagnostic workups are indicated based...

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