Onset is typically 1 to 3 weeks after initiation of drug.
Prodrome of fever, malaise, headache, sore throat, and conjunctivitis followed by skin lesions after 1 to 3 days (detailed bel...
Supportive care is still the mainstay of TEN treatment; withdrawal of offending drug agent, if known, is imperative.
Early transfer to an ICU/burn unit is critical because patients can rapidl...
Avoidance of inciting drug or drug class in the future
Monitoring of dermatologic and ocular sequelae
Skin reepithelialization usually occurs within 1 to 3...
Abe R. Immunological response in Stevens-Johnson syndrome and toxic epidermal necrolysis. J Dermatol. 2015;42(1):42–48. [View Abstract on OvidMedline]
Abela C, Hartmann CE, De ...
23067006 Lyell’s toxic epidermal necrolysis, subepidermal type (disorder)
402744003 toxic epidermal necro...
SJS and TEN are on a spectrum, with TEN the more severe disease.
Expert care in burn centers improves outcomes.
Sign up for a 10-day FREE Trial now and receive full access to all content.