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Tuberculosis, Latent (LTBI)

Laurel Banach, M.D. Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Latent tuberculosis infection (LTBI) is an asymptomatic, noninfectious condition following exposure to an active case of tuberculosis. LTBI is usually detected by a screening skin/bl...

DIAGNOSIS

HISTORY

  • Assess risk; history of immigration from a high-risk area including those with temporary visas for school or work (note: TB screening for this type of visa is not required, unlike reg...

TREATMENT

GENERAL MEASURES

  • Must first exclude Active TB by history, physical exam, and lung imaging. Chest x-ray must be obtained within two months prior to starting LTBI treatment.

  • Treatment for LTBI i...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • During treatment course for LTBI, monthly visits to assess adherence and monitor for signs and symptoms of active TP or signs of adverse treatme...

REFERENCES

1
World Health Organization. (‎2018)‎. Latent tuberculosis infection: updated and consolidated guidelines for programmatic management. https://apps.who.int/iris/handle/10665/260233.
2
Sterling...

ADDITIONAL READING

SEE ALSO

Tuberculosis; Tuberculosis, Miliary 

CODES

ICD10

R76.11 Nonspecific reaction to skin test w/o active tuberculosis 

SNOMED

11999007 inactive tuberculosis (disorder) 

CLINICAL PEARLS

  • Treatment of LTBI is crucial to the control and elimination of TB disease in the United States.

  • Screen persons from TB-endemic countries, and treat those who are positive.

  • Screen househo...

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