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Tuberculosis

Michael C. Stefanowicz, DO and Swati B. Avashia, MD, FAAP, FACP, ABIHM Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Active tuberculosis (TB)

    • Primary infection or reactivation of latent infection

    • Without preventive therapy, affects 10% of infected individuals

    • Risk increases with immunosuppression: H...

DIAGNOSIS

HISTORY

  • Known exposure to individual with active TB

  • Immunosuppression

  • Tobacco use; recreational drug use

  • Signs and symptoms

    • General: fever, night sweats, weight loss, malaise, painless lymph no...

TREATMENT

GENERAL MEASURES

  • If clinical suspicion, treat immediately. Prescribing physician is responsible for treatment completion.

  • Respiratory and droplet precautions

  • Not infectious if favorable clinica...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Monthly sputum for AFB smear and culture until two consecutive cultures are negative; must confirm this prior to starting continuation phase

  • Mont...

REFERENCES

1
World Health Organization. Global tuberculosis report 2016. http://www.who.int/tb/publications/global_report/gtbr2016_main_text.pdf?ua=1. Accessed July 9, 2017.
2
Schmit KM, Wansaula Z, Prat...

SEE ALSO

  • Tuberculosis, CNS; Tuberculosis, Latent (LTBI); Tuberculosis, Miliary

  • Algorithm: Weight Loss, Unintentional

CODES

ICD10

  • A15.9 Respiratory tuberculosis unspecified

  • A15.0 Tuberculosis of lung

  • A19.9 Miliary tuberculosis, unspecified

  • A18.89 Tuberculosis of other sites

  • A17.9 Tuberculosis of nervous system, unspecifie...

CLINICAL PEARLS

  • TB is fully curable when treated appropriately.

  • Children and elderly patients exhibit fewer classic clinical features of TB.

  • Involve public health authorities early.

  • Treatment of pulmonar...

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