Active tuberculosis (TB)
Primary infection or reactivation of latent infection
Without preventive therapy, affects 10% of infected individuals
Risk increases with immunosuppression: hig...
Known exposure to individual with active TB
Tobacco use; recreational drug use
Signs and symptoms
General: fever, night sweats, unintentional weight loss, malaise, painl...
If clinical suspicion, treat immediately. Prescribing physician is responsible for treatment completion.
Respiratory and droplet precautions
Not infectious if favorable clinica...
Monthly sputum for AFB smear and culture until two consecutive cultures are negative; must confirm this prior to starting continuation phase
Tuberculosis, CNS; Tuberculosis, Latent (LTBI); Tuberculosis, Miliary
Algorithm: Weight Loss, Unintentional
A15.9 Respiratory tuberculosis, unspecified
A15.0 Tuberculosis of lung
A19.9 Miliary tuberculosis, unspecified
A18.89 Tuberculosis of other sites
A17.9 Tuberculosis of nervous system, unspecifi...
TB is fully curable when treated appropriately.
Children and elderly patients exhibit fewer classic clinical features of TB.
TST and IGRA cannot discern active TB from LTBI.
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