Skip to main content

Typhoid Fever

Douglas William MacPherson, MD, MSc(CTM), FRCPC Reviewed 04/2024
 


BASICS

  • An uncommon enteric bacterial disease transmitted by ingestion of contaminated food or water

  • Most cases in the United States are imported from endemic areas of South or Southeast Asia and Latin ...

DIAGNOSIS

Assess clinical presentation and exposure history, including travel and exposures to S. typhi carriers. 

HISTORY

  • Travel history to an endemic region and exposure to contaminated food or water

  • E...

TREATMENT

  • Treatment of typhoid disease and chronic carrier states must be determined on an individual basis. Factors to consider include age, public health and occupational health risk (e.g., food han...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Bed rest initially and then activity as tolerated 

Patient Monitoring

See “General Measures.” 

DIET

NPO if abdominal symptoms are severe. With improvement, begin norm...

REFERENCES

1
Meiring JE, Khanam F, Bashnyat B, et al. Typhoid fever. Nat Rev Dis Primers. 2023;9(1):71. doi: 10.1038/s41572-023-00480-z. PMID: 38097589.
2
Appiah GD, Hughes MJ, Chatham-Stephens K. Typho...

ADDITIONAL READING

Marchello CS, Hong CY, Crump JA. Global Typhoid Fever Incidence: A Systematic Review and Meta-analysis. Clin Infect Dis. 2019;68(Suppl 2):S105-S116.  

CODES

ICD10

  • A01.00 Typhoid fever, unspecified

  • Z22.0 Carrier of typhoid

  • A01.03 Typhoid pneumonia

  • A01.09 Typhoid fever with other complications

SNOMED

  • 4834000 Typhoid fever (disorder)

  • 170484009 Typhoid carrier...

CLINICAL PEARLS

  • Consider typhoid (along with malaria, dengue, and other travel-associated infections) in febrile travelers returning from endemic areas (Latin America, sub-Saharan Africa, South Asia)....

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×