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Ulcer, Aphthous

Cynthia Y. Ohata, MD and Trent J. Auguston, MD Reviewed 06/2020
 


BASICS

DESCRIPTION

  • Self-limited, painful ulcerations of the nonkeratinized oral mucosa, which are often recurrent

  • Synonyms: canker sores; aphthae; aphthous stomatitis

    • Comes from aphth meaning “to set on ...

DIAGNOSIS

Diagnosis is made by history and clinical presentation. Lab work is rarely contributory (3)[A]. 

HISTORY

  • May experience prodrome of burning sensation of oral mucosa 2 to 48 hours prior to appe...

TREATMENT

GENERAL MEASURES

Management is symptomatic. Goal is to reduce inflammation and relieve pain. 

MEDICATION

In general, the goals of treatment depend on the extent of ulceration and frequency of o...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Evaluation for infection, mucocutaneous or systemic disease, or malignancy should be pursued for nonhealing lesions or lesions with lymphadenopathy or unusual pre...

REFERENCES

1
Edgar NR, Saleh D, Miller RA. Recurrent aphthous stomatitis: a review. J Clin Aesthet Dermatol.  2017;10(3):26–36.
2
Lehman JS, Rogers RSIII. Acute oral ulcers. Clin Dermatol.  201...

ADDITIONAL READING

  • Lalla RV, Choquette LE, Feinn RS, et al. Multivitamin therapy for recurrent aphthous stomatitis: a randomized, double-masked, placebo-controlled trial. J Am Dent Assoc.  2012;1...

CODES

ICD10

K12.0 Recurrent oral aphthae 

ICD9

528.2 Oral aphthae 

SNOMED

  • 426965005 aphthous ulcer of mouth (disorder)

  • 307772002 Minor oral aphthous ulceration (disorder)

  • 196531008 Major aphthous ulceration ...

CLINICAL PEARLS

  • Aphthous ulcers are the most common chronic disease of the oral cavity.

  • Most cases are mild, self-limited episodes.

  • Appropriate treatment should be aimed at symptom control and promotion...

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