Vitamin deficiency related to inadequate intake or absorption of cobalamin (vitamin B12)
Cobalamin is critical for CNS myelination and normal functioning.
Deficiency can cause a multitude of symp...
Asymptomatic patients may be diagnosed by the incidental finding of anemia or an elevated mean corpuscular volume (MCV) during routine testing or evaluat...
Parenteral cyanocobalamin replacement recommended in patients with severe neurologic symptoms: IM cyanocobalamin (2)[C]
1,000 μg/day for 7 days, then
1,000 μg weekly for 4 weeks, t...
Hematologic
Reticulocytosis in 1 week
Rise in hemoglobin beginning at 10 days; usually will return to normal in 6 to 8 weeks
Monitor potassium in...
Allen LH. How common is vitamin B-12 deficiency? Am J Clin Nutr. 2009;89(2):693S–696S. [View Abstract on OvidMedline]
Aroda VR, Edelstein SL, Goldberg RB, et al; Diabetes Prev...
E53.8 Deficiency of other specified B group vitamins
D51.0 Vitamin B12 defic anemia due to intrinsic factor deficiency
D51.3 Other dietary vitamin B12 deficiency anemia
D51.1 Vitamin B12 defic...
Consider screening for B12 deficiency in high-risk patients including the elderly and monitoring B12 levels annually if on metformin or on chronic PPIs.
Correcting folate deficiency wit...
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