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Vitiligo

Reviewed 06/2018
 


BASICS

DESCRIPTION

  • An acquired depigmentation of the skin, which correlates with a loss of epidermal melanocytes. There are three clinical variants, each with subtypes.

  • Localized: often in childhood, ra...

DIAGNOSIS

HISTORY

  • Inquire about recent history of sunburns, pregnancy, skin trauma, or emotional stress.

  • Family history of premature graying, vitiligo, and autoimmune disorders

  • Review of systems for rela...

TREATMENT

The variant of vitiligo may affect response. 
  • If untreated, progression is the natural course for those with mucosal involvement, family history, koebnerization, and nonsegmental variants.

  • Les...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

  • Monitor for symptoms of related conditions.

  • With topical steroids, follow at regular intervals to avoid steroid atrophy, telangiectasia, and striae distensae.

DIET

N...

REFERENCES

1
Ezzedine K, Eleftheriadou V, Whitton M, et al. Vitiligo. Lancet.  2015;386(9988):74–84. [View Abstract on OvidMedline]
2
Colucci R, Lotti T, Moretti S. Vitiligo: an update on current p...

ADDITIONAL READING

  • Alikhan A, Felsten LM, Daly M, et al. Vitiligo: a comprehensive overview part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histop...

CODES

ICD10

L80 Vitiligo 

ICD9

709.01 Vitiligo 

SNOMED

  • 56727007 Vitiligo (disorder)

  • 403267005 Localized vitiligo

  • 403269008 Generalized vitiligo (disorder)

  • 403268000 Segmental vitiligo

  • 238713002 Occupational vi...

CLINICAL PEARLS

  • Vitiligo can be a psychologically devastating skin disease.

  • Screen for associated diseases, particularly if onset occurs later in life.

  • Treatment should be individualized based on BSA, s...

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