An acquired depigmentation of the skin, which correlates with a loss of epidermal melanocytes. There are two major clinical variants, each with subtypes.
Nonsegmental vitiligo: Depigm...
Inquire about recent history of sunburns, pregnancy, skin trauma, or emotional stress.
Discuss family history of premature graying, vitiligo, and autoimmune disorders.
Complete a review...
If untreated, progression is the natural course for those with mucosal involvement, family history, koebnerization, and nonsegmental variants.
Les...
Monitor for symptoms of related conditions.
With topical steroids, follow at regular intervals to avoid steroid atrophy, telangiectasia, and striae distensae.
Bergqvist C, Ezzedine K. Vitiligo: A Review. Dermatology. 2020;236(6):571-592. doi: 10.1159/000506103. PMID: 32155629.
Kussainova A, Kassim L, Akhmeto...
L80 Vitiligo
H02.739 Vitiligo of unspecified eye, unspecified eyelid and periocular area
H02.735 Vitiligo of left lower eyelid and periocular area
H02.732 Vitiligo of right lower eyelid and pe...
Vitiligo can be a psychologically devastating skin disease.
Screen for associated diseases, particularly if onset occurs later in life.
Treatment should be individualized based on BSA, s...
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Segmental vitiligo: anterior trunk
Albinism and Vitiligo. Albinism is caused by a congenital inability to synthesize melanin as a result of genetic defects in the biochemical pathway that manufactures melanin. Vitiligo is a result of melanin loss in patchy areas of the skin. It develops after birth and is progessive (brown pigment on legs is patient's normal skin color).
Albinism and Vitiligo. Albinism is caused by a congenital inability to synthesize melanin as a result of genetic defects in the biochemica...
FIGURE 21-10. Vitiligo. Depigmented macules appear on the skin and may merge into large areas that lack melanin. The brown pigment seen in the illustration is the person?s normal skin color; the pale areas are caused by vitiligo. (Reprinted with permission from Bickley LS. Bate's Guide to Physical Examination and History Taking. 8th Ed. Philadelphia: Lippincott Williams & Wilkins, 2003.)
FIGURE 21-10. Vitiligo. Depigmented macules appear on the skin and may merge into large areas that lack melanin. The brown pigment seen in...
Vitiligo at the wrist skin of the left hand in a 42-year-old man who had developed Vogt-Koyanagi-Harada syndrome 8 months before.
Area of depigmentation of skin surrounding the eye in a patient with vitiligo associated with severe iritis.
Closer view of area of skin depigmentation. Note associated whitening of lashes (poliosis).
Vitiligo. Various shades of hypopigmentation, depigmentation, and islands of spontaneous repigmentation can be seen in this patient. Note the white eyelashes. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagnosis and Management, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2009.
Vitiligo. Various shades of hypopigmentation, depigmentation, and islands of spontaneous repigmentation can be seen in this patient. Note t...
Vitiligo. Extensive depigmentation is evident in this patient. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagnosis and Management, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2009.
Vitiligo. Extensive depigmentation is evident in this patient. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagnosi...
Vitiligo. Wood's lamp examination reveals a “milk-white” fluorescence in areas depigmented by vitiligo. Note the depigmented eyebrows and eyelashes. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagnosis and Management, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2009.
Vitiligo. Wood's lamp examination reveals a “milk-white” fluorescence in areas depigmented by vitiligo. Note the depigmented eyebrows and e...
Vitiligo. Note the complete depigmentation and the lack of scale. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagnosis and Management, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2009.
Vitiligo. Note the complete depigmentation and the lack of scale. From Goodheart HP. Goodheart's Photoguide to Common Skin Disorders: Diagn...