Skip to main content

Vulvar Malignancy

Christina N. Kufel, DO, MS and Michael P. Hopkins, MD, MEd Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Premalignant lesions of the vulva are collectively known as vulvar intraepithelial neoplasia (VIN). Exposure to human papillomavirus (HPV) has been linked to >70% of VIN.

  • Invasive ...

DIAGNOSIS

HISTORY

Complaints of pruritus or raised lesion in the vaginal area, vaginal bleeding, discharge 

PHYSICAL EXAM

  • In situ disease: a small raised area associated with pruritus, single vulvar plaq...

TREATMENT

GENERAL MEASURES

  • Wide excision can be performed for carcinoma in situ, and any suspicious lesion should be excised for definitive diagnosis.

  • Cystoscopy and sigmoidoscopy should be performed if...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Early stage, treated with surgery alone: clinical exam of the groin nodes and vulvar area every 6 months for 2 years; then annually

  • Following che...

REFERENCES

1
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin.  2015;65(1):5–29. [View Abstract on OvidMedline]
2
Hacker N, Eifel P, van der Velden J. Cancer of the vulva. I...

CODES

ICD10

  • C51.9 Malignant neoplasm of vulva, unspecified

  • D07.1 Carcinoma in situ of vulva

  • C51.0 Malignant neoplasm of labium majus

  • C51.1 Malignant neoplasm of labium minus

  • C51.8 Malignant neoplasm of ove...

CLINICAL PEARLS

  • 55% of vulvar cancers are attributable to oncogenic HPV and 92% of all VIN 2/3, VAIN 2/3, and AIN are attributable to HPV. Therefore, HPV vaccination has the potential to decrease vulv...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×