The most common renal tumor in children; fifth most common pediatric malignancy
An embryonal renal neoplasm containing blastemal, stromal, or epithelial cell types
System(s) affected: ...
Most WT patients present with asymptomatic abdominal mass (>90%) (1).
Abdominal pain (40%), hypertension (25%), microscopic (24%) or gross hematuria (18%) (1)
Associated symptoms (...
Treatment differs between
Treatment consists of surgical resection with varying regimens of combination chemotherapy and radiation therapy dependent upon stage of disease.
Risk...
Monitoring for toxic effects of therapy should be performed throughout treatment and long-term: liver function tests; serum creatinine; CBC; ECH...
C64.9 Malignant neoplasm of unsp kidney, except renal pelvis
C64.1 Malignant neoplasm of right kidney, except renal pelvis
C64.2 Malignant neoplasm of left kidney, except renal pelvis
30...
WT is the most common renal tumor in children; usually affecting children <5 years.
Overall survival 30-100%.
Outcomes worse with anaplasia, older age, advanced stage, chromosome gain...
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Wilms tumor. A cross-section of a pale tan neoplasm is attached to a residual portion of the kidney.
<bold>Fig GU 32-7. Wilms' tumor.</bold> Large low-density mass pushing the functioning portion of the left kidney (arrow) across the midline.
<bold>Fig GU 32-7. Wilms' tumor.</bold> Large low-density mass pushing the functioning portion of the left kidney (arrow) acro...
<bold>Fig GU 32-8. Bilateral Wilms' tumor.</bold> Huge left renal mass (W) that crosses the midline. There is also a small separate mass (w) in the right kidney.<sup>2</sup>
<bold>Fig GU 32-8. Bilateral Wilms' tumor.</bold> Huge left renal mass (W) that crosses the midline. There is also a small sep...
<bold>Figure 9.44. Wilms tumor in two patients. A.</bold> IVU shows a mass in the left kidney distorting the renal architecture. <bold>B.</bold> Digital abdominal scout view for a CT scan on another patient shows upward displacement of the contrast in the right kidney (<i>arrow</i>). The abdomen appears to be filled with a mass.
<bold>Figure 9.44. Wilms tumor in two patients. A.</bold> IVU shows a mass in the left kidney distorting the renal architectur...
<bold>Figure 9.45. Wilms tumor of the left kidney.</bold> (This is the same patient as in Fig. 9.44B). Two CT images show the large right renal mass (<i>W</i>). Notice the beak sign at the junction of the tumor with normal kidney in B (<i>arrow</i>).
<bold>Figure 9.45. Wilms tumor of the left kidney.</bold> (This is the same patient as in Fig. 9.44B). Two CT images show the ...
<bold>Figure 9.45. Wilms tumor of the left kidney.</bold> (This is the same patient as in Fig. 9.44B). Two CT images show the large right renal mass (<italic>W</bold>). Notice the "beak" sign at the junction of the tumor with normal kidney in B (<italic>arrow</bold>).
<bold>FIGURE 112.6</bold> Wilms tumor (nephroblastoma). This photomicrograph of the tumor shows highly cellular areas composed of undifferentiated blastema, loose stroma containing undifferentiated mesenchymal cells, and immature tubules. (From Rubin E, Farber JL. <italic>Pathology</bold>, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 1999,with permission.)
<bold>FIGURE 112.6</bold> Wilms tumor (nephroblastoma). This photomicrograph of the tumor shows highly cellular areas composed...